Recombinant Human ATXN3L, His-tagged

• Cat.No.: ATXN3L-164H
• Product Overview: Recombinant Human ATXN3L protein, fused with His6 tag, was expressed in E. coli.

Specification

• Source: E. coli
• Species: Human
• Tag: His
• Form: Liquid
• Molecular Mass: 41kDa
• Storage: Store at -80°C, avoiding repeated freeze-thaw cycles.

Gene Information

• Gene Name: ATXN3L ataxin 3-like [ Homo sapiens ]
• Official Symbol: ATXN3L
• Synonyms: ataxin 3-like; ATX3L; MJDL; EC 3.4.19.12; Machado-Joseph disease protein 1-like; EC 3.4.22; putative ataxin-3-like protein
• Gene ID: 92552
• mRNA Refseq: NM_001135995.1
• Protein Refseq: NP_001129467.1
• UniProt ID: B4DYC7
• Chromosome Location: Xp22.2
• Pathway: Protein processing in endoplasmic reticulum, organism-specific biosystem; Protein processing in endoplasmic reticulum, conserved biosystem
• Function: omega peptidase activity; ubiquitin-specific protease activity

Reviews

07/10/2021

Unmatched reproducibility of ATXN3L, with consistent results from experiment to experiment or application, makes it ideal for use in experiments or applications that require a high degree of reproducibility.

04/20/2021

This production process of ATXN3L is very environmentally friendly, without any harmful by-products and without any negative impact on the environment.

02/09/2019

The short half-life and high clearance properties of this recombinant protein make it a higher potential in drug development and is expected to become a new generation of therapeutic drugs.

Q&As

How does the ATXN3L protein interact with other proteins?

ATXN3L protein interacts with multiple proteins, including heat shock proteins, ubiquitin ligases and other regulatory proteins.

What is the regulatory mechanism of ATXN3L protein?

The expression and function of ATXN3L protein are affected by multiple regulatory mechanisms, including transcriptional regulation, post-translational modification, and protein-protein interaction.

What is the function of ATXN3L protein?

The protein plays a role in regulating protein degradation in cells, and participates in the process of cell quality control and waste protein degradation.

What diseases is ATXN3L involved in?

This protein is associated with nervous system related diseases, including Parkinson's disease, Alzheimer's disease and so on.

What are the structural features of ATXN3L protein?

The ATXN3L protein contains multiple functional domains, including multiple polyglutamic acid repeats, which may be involved in protein interactions and regulation of function.

How is ATXN3L protein expressed?

ATXN3L protein is expressed in various tissues of the human body, but its expression is higher in the central nervous system.