Recombinant Human AXL, Fc-tagged

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Recombinant Human AXL, Fc-tagged

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Cat.No. : AXL-538H
Product Overview : The recombinant human AXL-Fc fusion is expressed as a 650 amino acid protein consisting of Ala26 - Ser447 region of AXL and a C-terminal Fc from human IgG1, which exists as a dimer under non-reducing conditions.
Source : Human cells
Species : Human
Tag : Fc
Form : Supplied at 0.5 mg/ml in sterile PBS pH7.4 (carrier free).
Bio-activity : Interacts with human Gas6 and inhibits Gas6/AXLmediated signaling activity.
Molecular Mass : Calculated molecular mass (kDa): 71.1; Estimated by SDS-PAGE under reducing condition (kDa): 80-90
AA Sequence : APRGTQAEES PFVGNPGNIT GARGLTGTLR CQLQVQGEPP EVHWLRDGQI LELADSTQTQ VPLGEDEQDD WIVVSQLRIT SLQLSDTGQY QCLVFLGHQT FVSQPGYVGL EGLPYFLEEP EDRTVAANTP FNLSCQAQGP PEPVDLLWLQ DAVPLATAPG HGPQRSLHVP GLNKTSSFSC EAHNAKGVTT SRTATITVLP QQPRNLHLVS RQPTELEVAW TPGLSGIYPL THCTLQAVLS DDGMGIQAGE PDPPEEPLTS QASVPPHQLR LGSLHPHTPY HIRVACTSSQ GPSSWTHWLP VETPEGVPLG PPENISATRN GSQAFVHWQE PRAPLQGTLL GYRLAYQGQD TPEVLMDIGL RQEVTLELQG DGSVSNLTVC VAAYTAAGDG PWSLPVPLEA WRPGQAQPVH QLVKEPSTPA FSSTGTHTCP PCPAPELLGG PSVFLFPPKP KDTLMISRTP EVTCVVVDVS HEDPEVKFNW YVDGVEVHNA KTKPREEQYN STYRVVSVLT VLHQDWLNGK EYKCKVSNKA LPAPIEKTIS KAKGQPREPQ VYTLPPSREE MTKNQVSLTC LVKGFYPSDI AVEWESNGQP ENNYKTTPPV LDSDGSFFLY SKLTVDKSRW QQGNVFSCSV MHEALHNHYT QKSLSLSPGK
Endotoxin : <0.1 eu per 1 μg of purified recombinant protein determined by the
Purity : >95% judged by SDS-PAGE under reducing condition
Storage : The product is shipped at 4°C. Upon receipt, centrifuge the product briefly before opening the vial. It is recommended to store small aliquots at the temperature below –20°C for long-term storage and the product is stable for 3 months. The undiluted protein can be stored at 4°C for no more than 2 weeks. Avoid repeated freeze-thaw cycles.
Gene Name : AXL AXL receptor tyrosine kinase [ Homo sapiens ]
Official Symbol : AXL
Synonyms : AXL; AXL receptor tyrosine kinase; tyrosine-protein kinase receptor UFO; JTK11; UFO; AXL oncogene; oncogene AXL; AXL transforming sequence/gene;
Gene ID : 558
mRNA Refseq : NM_001699
Protein Refseq : NP_001690
MIM : 109135
UniProt ID : P30530
Chromosome Location : 19q13.1
Function : ATP binding; nucleotide binding; protein heterodimerization activity; receptor activity; transmembrane receptor protein tyrosine kinase activity;
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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