Recombinant Human CD27, Fc-tagged, Biotinylated CD27-564H

Recombinant Human CD27, Fc-tagged, Biotinylated

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Recombinant Human CD27, Fc-tagged, Biotinylated

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Cat.No. : CD27-564H
Product Overview : The recombinant human CD27-Fc fusion is expressed as a 400 amino acid protein consisting of Ala20 - Arg191 region of CD27 (UniProt accession #P26842) and a C-terminal Fc from human IgG1, which exists as a dimer under non-reducing conditions.
Source : Human cells
Species : Human
Tag : Fc
Form : Supplied at 0.5 mg/ml in sterile PBS pH7.4 (carrier & preservative free). The purified recombinant protein was labeled with Biotin (3-5 Biotin per molecule).
Bio-activity : Binds to its ligand CD70 and inhibits CD70-mediated signaling activities including proliferation of T cells induced by CD70 and anti-CD3 antibody.
Molecular Mass : Calculated molecular mass (kDa): 44.8; Estimated by SDS-PAGE under reducing condition (kDa): 65-70
Endotoxin : <0.1 eu per 1 μg of purified recombinant protein determined by the
Purity : >95% judged by SDS-PAGE under reducing condition
Storage : The product is shipped at 4°C. Upon receipt, centrifuge the product briefly before opening the vial. It is recommended to store small aliquots at the temperature below –20°C for long-term storage and the product is stable for 3 months. The undiluted protein can be stored at 4°C for no more than 2 weeks. Avoid repeated freeze-thaw cycles.
Gene Name : CD27 CD27 molecule [ Homo sapiens ]
Official Symbol : CD27
Synonyms : CD27; CD27 molecule; TNFRSF7, tumor necrosis factor receptor superfamily, member 7; CD27 antigen; S152; Tp55; CD27L receptor; T cell activation antigen S152; T-cell activation antigen CD27; tumor necrosis factor receptor superfamily, member 7; T14; TNFRSF7; MGC20393;
Gene ID : 939
mRNA Refseq : NM_001242
Protein Refseq : NP_001233
MIM : 186711
UniProt ID : P26842
Chromosome Location : 12p13
Pathway : Cytokine-cytokine receptor interaction, organism-specific biosystem; Cytokine-cytokine receptor interaction, conserved biosystem;
Function : cysteine-type endopeptidase inhibitor activity involved in apoptotic process; protein binding; receptor activity; transmembrane signaling receptor activity;

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