"TNFRSF10C" Related Products


Recombinant Human TNFRSF10C, Fc-tagged, Biotinylated

Cat.No.: TNFRSF10C-594H
Product Overview: The recombinant human DcR1-Fc fusion is expressed as a 438 amino acid protein consisting of Ala26 - Pro235 region of DcR1 (UniProt accession #O14798) and a C-terminal Fc from human IgG1, which exists as a dimer under non-reducing conditions.
Source: Human cells
Species: Human
Tag: Fc
Form: Supplied at 0.5 mg/ml in sterile PBS pH7.4 (carrier & preservative free). The purified recombinant protein was labeled with Biotin (3-5 Biotin per molecule).
Bio-activity: Binds to its ligand human TRAIL and inhibits TRAIL-mediated signaling activity including TRAIL-induced cytotoxicity in L-929 mouse fibroblast cells.
Molecular Mass: Calculated molecular mass (kDa): 47.7; Estimated by SDS-PAGE under reducing condition (kDa): 65-75
Endotoxin: <0.1 eu per 1 μg of purified recombinant protein determined by the
Purity: >95% judged by SDS-PAGE under reducing condition
Storage: The product is shipped at 4°C. Upon receipt, centrifuge the product briefly before opening the vial. It is recommended to store small aliquots at the temperature below –20°C for long-term storage and the product is stable for 3 months. The undiluted protein can be stored at 4°C for no more than 2 weeks. Avoid repeated freeze-thaw cycles.
Gene Name: TNFRSF10C tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain [ Homo sapiens ]
Official Symbol: TNFRSF10C
Synonyms: TNFRSF10C; tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain; tumor necrosis factor receptor superfamily member 10C; CD263; DcR1; LIT; TRAILR3; TRID; decoy receptor 1; cytotoxic TRAIL receptor-3; lymphocyte inhibitor of TRAIL; decoy TRAIL receptor without death domain; antagonist decoy receptor for TRAIL/Apo-2L; TNF-related apoptosis-inducing ligand receptor 3; DCR1; TRAIL-R3; DCR1-TNFR; MGC149501; MGC149502;
Gene ID: 8794
mRNA Refseq: NM_003841
Protein Refseq: NP_003832
MIM: 603613
UniProt ID: O14798
Chromosome Location: 8p22-p21
Pathway: Apoptosis, organism-specific biosystem; Apoptosis, conserved biosystem; Cytokine-cytokine receptor interaction, organism-specific biosystem; Cytokine-cytokine receptor interaction, conserved biosystem; Direct p53 effectors, organism-specific biosystem; Influenza A, organism-specific biosystem; Influenza A, conserved biosystem;
Function: TRAIL binding; binding; receptor activity; transmembrane signaling receptor activity;

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