Recombinant Human FAS, Fc-tagged, Biotinylated FAS-603H

Recombinant Human FAS, Fc-tagged, Biotinylated

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Recombinant Human FAS, Fc-tagged, Biotinylated

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Cat.No. : FAS-603H
Product Overview : The recombinant human Fas-Fc fusion is expressed as a 376 amino acid protein consisting of Gln26 - Asn173 region of Fas (UniProt accession #P25445) and a C-terminal Fc from human IgG1, which exists as a dimer under non-reducing conditions
Source : Human cells
Species : Human
Tag : Fc
Form : Supplied at 0.5 mg/ml in sterile PBS pH7.4 (carrier & preservative free). The purified recombinant protein was labeled with Biotin (3-5 Biotin per molecule).
Bio-activity : Binds to its ligand FasL and inhibits FasL-induced apoptosis in human acute T cell leukemia Jurkat cells.
Molecular Mass : Calculated molecular mass (kDa): 42.2; Estimated by SDS-PAGE under reducing condition (kDa): 55-60
Endotoxin : <0.1 eu per 1 μg of purified recombinant protein determined by the
Purity : >95% judged by SDS-PAGE under reducing condition
Storage : The product is shipped at 4°C. Upon receipt, centrifuge the product briefly before opening the vial. It is recommended to store small aliquots at the temperature below –20°C for long-term storage and the product is stable for 3 months. The undiluted protein can be stored at 4°C for no more than 2 weeks. Avoid repeated freeze-thaw cycles.
Gene Name : FAS Fas (TNF receptor superfamily, member 6) [ Homo sapiens ]
Official Symbol : FAS
Synonyms : FAS; Fas (TNF receptor superfamily, member 6); APT1, FAS1, TNFRSF6, tumor necrosis factor receptor superfamily, member 6; tumor necrosis factor receptor superfamily member 6; APO 1; CD95; Fas AMA; FAS 827dupA; CD95 antigen; FASLG receptor; apoptosis antigen 1; Delta Fas/APO-1/CD95; APO-1 cell surface antigen; apoptosis-mediating surface antigen FAS; tumor necrosis factor receptor superfamily, member 6; APT1; FAS1; APO-1; FASTM; ALPS1A; TNFRSF6;
Gene ID : 355
mRNA Refseq : NM_000043
Protein Refseq : NP_000034
MIM : 134637
UniProt ID : P25445
Chromosome Location : 10q24.1
Pathway : Activation of Pro-Caspase 8, organism-specific biosystem; Adipogenesis, organism-specific biosystem; African trypanosomiasis, organism-specific biosystem; African trypanosomiasis, conserved biosystem; Allograft rejection, organism-specific biosystem; Allograft rejection, conserved biosystem; Alzheimers disease, organism-specific biosystem;
Function : binding; identical protein binding; kinase binding; protein binding; receptor activity; receptor activity; signal transducer activity; transmembrane signaling receptor activity; tumor necrosis factor-activated receptor activity;

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