Recombinant Human KDM6B, Flag-tagged


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Recombinant Human KDM6B, Flag-tagged

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Cat.No. : KDM6B-562H
Product Overview : Recombinant Human KDM6B(a.a: 1043–end) fussed with Flag tag at C-terminal was expressed in Sf9 insect cells.
Description : Human KDM6B also known as lysine (K)-specific demethylase 6B, plays a very improtant role in many path ways.
Source : Insect cells
Species : Human
Tag : Flag
Form : 45 mM Tris-HCl, pH 8.0, 124 mM NaCl, 2.4 mM KCl, 90 µg/ml FLAG peptide, 10% glycerol, and 3 mM DTT.
Bio-activity : 0.022 pmole/min/μg
Molecular Mass : MW=71 kDa
Applications : Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling.
Stability : >6 months at –80 centigrade.
Warning : Avoid freeze/thaw cycles.
Gene Name : KDM6B lysine (K)-specific demethylase 6B [ Homo sapiens ]
Official Symbol : KDM6B
Synonyms : JMJD3; lysine-specific demethylase 6B; jmjC domain-containing protein 3; jumonji domain containing 3, histone lysine demethylase; jumonji domain-containing protein 3; lysine demethylase 6B
Gene ID : 23135
mRNA Refseq : NM_001080424
Protein Refseq : NP_001073893
MIM : 611577
UniProt ID : O15054
Chromosome Location : 17p13.1
Pathway : Cellular Senescence, organism-specific biosystem; Chromatin modifying enzymes, organism-specific biosystem; HDMs demethylate histones, organism-specific biosystem
Function : beta-catenin binding; histone demethylase activity (H3-K27 specific); metal ion binding
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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