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Active Native Sheep Stimulating Hormone

Cat.No. : FSH-1565S
Product Overview : Two-chain glycoprotein hormone. The α-chain is not active; biological specificity is attributed to the β-chain. Induces maturation of Graafian follicles of the ovary; promotes development of germinal cells in males; activates cytosolic tyrosine kinase. CAS number is 9002-68-0.
  • Specification
  • Gene Information
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Source : sheep pituitary
Species : Sheep
Form : White Powder
Bio-activity : 50 units per vial by the Steelman-Pohley Assay using NIH-FSH-S1 reference standard.
Storage : Storage Temperature: 2 - 8 °C.

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (10)

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In which stage of follicular growth is FSH most abundant? 04/14/2023

lipid metabolism pathways were significantly enriched in DEGs among 3 follicular development stages in FSH superstimulation.

To which hormones is FSH structurally similar? 04/14/2023

Structural similarity with other glycoprotein hormones of pituitary and placental origin such as luteinizing hormone (LH), thyroid-stimulating hormone (TSH), and human choriogonadotropin hormone (hCG).

Since there are different chemical isomers of FSHR, can they all bind FSH? 04/14/2023

These glycoforms have been shown to have differential functional effects in in vitro studies.

Does FSH promote angiogenesis? 04/14/2023

FSH-FSHR signaling can promotes angiogenesis.

What is the mechanism by which FSH promotes osteogenesis? 04/14/2023

FSH has been identified to stimulate release of IL-1ß, which increases the length of survival time of osteoclasts causing further bone resorption to occur.

In what different types of tumors can FSH receptors be expressed? 04/14/2023

Accumulating body of evidence demonstrates that FSHR is expressed in different types of tumors, such as: prostate, ovarian, thyroid, neuroendocrine, pancreatic, pituitary, and soft tissue sarcomas.

By which receptor is the biological function of FSH activated? 04/14/2023

Biological functions of FSH are activated through its interaction with its specific receptors (i.e. FSHR1).

The functional specificity of FSH is determined by which of its own structures? 04/14/2023

Functional specificity of FSH is provided by its β-subunit that ensures FSH interaction specifically with FSH receptor (FSHR).

What is Follicle Stimulating Hormone? 04/14/2023

FSH is a glycoprotein and plays an important role in: growth, development, pubertal maturation, and reproductive physiology.

How is FSH synthesized in the body? 04/14/2023

Gonadotrophs of the anterior pituitary gland synthesize and secrete follicle stimulating hormone (FSH) in response to stimulation by the hypothalamic gonadotropin releasing hormone.

Customer Reviews (5)

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Reviews
12/11/2022

    High efficiency for horseradish peroxidase labeling.

    11/14/2021

      Successfully used for Pull-down assay.

      12/11/2020

        Useful in biolayer interferometry.

        06/15/2020

          Useful in computational and crystallographic studies.

          02/19/2017

            Good for Co-IP control.

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