Recombinant Human FOXC2 protein, MYC/DDK-tagged

• Cat.No.: FOXC2-6160H
• Product Overview: Recombinant Human FOXC2, fussed with MYC/DDK tag at C-terminal, was expressed in HEK293 cells.

Specification

• Description: This gene belongs to the forkhead family of transcription factors which is characterized by a distinct DNA-binding forkhead domain. The specific function of this gene has not yet been determined; however, it may play a role in the development of mesenchymal tissues.
• Source: HEK293
• Species: Human
• Tag: MYC/DDK
• Form: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 53.5 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Notes: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
• Concentration: >50 ug/mL as determined by microplate BCA method

Gene Information

• Gene Name: FOXC2 forkhead box C2 (MFH-1, mesenchyme forkhead 1) [ Homo sapiens ]
• Official Symbol: FOXC2
• Synonyms: FOXC2; forkhead box C2 (MFH-1, mesenchyme forkhead 1); FKHL14; forkhead box protein C2; MFH 1; MFH-1,mesenchyme forkhead 1; transcription factor FKH-14; mesenchyme fork head protein 1; forkhead-related protein FKHL14; forkhead, Drosophila, homolog-like 14; LD; MFH1; MFH-1
• Gene ID: 2303
• mRNA Refseq: NM_005251
• Protein Refseq: NP_005242
• MIM: 602402
• UniProt ID: Q99958
• Chromosome Location: 16q24.1
• Pathway: Adipogenesis, organism-specific biosystem; Heart Development, organism-specific biosystem
• Function: DNA binding, bending; RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; chromatin DNA binding; double-stranded DNA binding; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; sequence-specific distal enhancer binding RNA polymerase II transcription factor activity; transcription factor binding; transcription regulatory region DNA binding