Active Recombinant Human TNFRSF11B, Fc-tagged, Biotinylated
Cat.No. : | TNFRSF11B-654H |
Product Overview : | The recombinant human OPG-Fc fusion is expressed as a 608 amino acid protein consisting of Glu22 - Leu401 region of OPG (UniProt accession #O00300) and a C-terminal Fc from human IgG1, which exists as a dimer under non-reducing conditions. |
- Specification
- Gene Information
- Related Products
Source : | Human cells |
Species : | Human |
Tag : | Fc |
Form : | Supplied at 0.5 mg/ml in sterile PBS pH7.4 (carrier & preservative free). The purified recombinant protein was labeled with Biotin (3-5 Biotin per molecule). |
Bio-activity : | Binds to its ligands TRAIL and RANKL. Inhibits TRAIL- and RANKL-mediated signaling activity including NF-kB activation and TRAIL-induced cytotoxicity in L-929 mouse fibroblast cells. |
Molecular Mass : | Calculated molecular mass (kDa): 69.2; Estimated by SDS-PAGE under reducing condition (kDa): 75-85 |
Endotoxin : | <0.1 eu per 1 μg of purified recombinant protein determined by the lal>0.1> |
Purity : | >95% judged by SDS-PAGE under reducing condition |
Storage : | The product is shipped at 4°C. Upon receipt, centrifuge the product briefly before opening the vial. It is recommended to store small aliquots at the temperature below –20°C for long-term storage and the product is stable for 3 months. The undiluted protein can be stored at 4°C for no more than 2 weeks. Avoid repeated freeze-thaw cycles. |
Gene Name : | TNFRSF11B tumor necrosis factor receptor superfamily, member 11b [ Homo sapiens ] |
Official Symbol : | TNFRSF11B |
Synonyms : | TNFRSF11B; tumor necrosis factor receptor superfamily, member 11b; OPG, osteoprotegerin; tumor necrosis factor receptor superfamily member 11B; OCIF; TR1; osteoprotegerin; osteoclastogenesis inhibitory factor; OPG; MGC29565; |
Gene ID : | 4982 |
mRNA Refseq : | NM_002546 |
Protein Refseq : | NP_002537 |
MIM : | 602643 |
UniProt ID : | O00300 |
Chromosome Location : | 8q24 |
Pathway : | Cytokine-cytokine receptor interaction, organism-specific biosystem; Cytokine-cytokine receptor interaction, conserved biosystem; Monoamine Transport, organism-specific biosystem; Osteoblast Signaling, organism-specific biosystem; Osteoclast Signaling, organism-specific biosystem; Osteoclast differentiation, organism-specific biosystem; Osteoclast differentiation, conserved biosystem; |
Function : | binding; cytokine activity; receptor activity; |
Products Types
◆ Recombinant Protein | ||
TNFRSF11B-830H | Recombinant Human TNFRSF11B Protein, Fc-tagged | +Inquiry |
TNFRSF11B-365H | Recombinant Human TNFRSF11B Protein (Met1-Leu401), HIgG1 Fc-tagged | +Inquiry |
TNFRSF11B-1162P | Recombinant Pig TNFRSF11B Protein, His-tagged | +Inquiry |
TNFRSF11B-5853R | Recombinant Rat TNFRSF11B Protein, His (Fc)-Avi-tagged | +Inquiry |
TNFRSF11B-2455H | Recombinant Human TNFRSF11B protein(22-401 aa), N-MBP & C-His-tagged | +Inquiry |
◆ Native Protein | ||
TNFRSF11B-54H | Native Human Osteoprotegerin | +Inquiry |
◆ Lysates | ||
TNFRSF11B-1183CCL | Recombinant Cynomolgus TNFRSF11B cell lysate | +Inquiry |
TNFRSF11B-2176HCL | Recombinant Human TNFRSF11B cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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