"TNFRSF13B" Related Products

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Recombinant Human TNFRSF13B, Fc-tagged, Biotinylated

Cat.No.: TNFRSF13B-693H
Product Overview: The recombinant human TACI-Fc fusion is expressed as a 391 amino acid protein consisting of Ser2 - Ser165 region of TACI (UniProt accession #O14836) and a C-terminal Fc from human IgG1, which exists as a dimer under non-reducing conditions.
Source: Human cells
Species: Human
Tag: Fc
Form: Supplied at 0.5 mg/ml in sterile PBS pH7.4 (carrier & preservative free). The purified recombinant protein was labeled with Biotin (3-5 Biotin per molecule).
Bio-activity: Binds to its ligand BAFF. Inhibits BAFF-mediated signaling activities including NF-κB activation and proliferation of anti-IgM co-stimulated B cells.
Molecular Mass: Calculated molecular mass (kDa): 43.9; Estimated by SDS-PAGE under reducing condition (kDa): 45-50
Endotoxin: <0.1 eu per 1 μg of purified recombinant protein determined by the lal>
Purity: >95% judged by SDS-PAGE under reducing condition
Storage: The product is shipped at 4°C. Upon receipt, centrifuge the product briefly before opening the vial. It is recommended to store small aliquots at the temperature below –20°C for long-term storage and the product is stable for 3 months. The undiluted protein can be stored at 4°C for no more than 2 weeks. Avoid repeated freeze-thaw cycles.
Gene Name: TNFRSF13B tumor necrosis factor receptor superfamily, member 13B [ Homo sapiens ]
Official Symbol: TNFRSF13B
Synonyms: TNFRSF13B; tumor necrosis factor receptor superfamily, member 13B; tumor necrosis factor receptor superfamily member 13B; CD267; TACI; tumor necrosis factor receptor 13B; transmembrane activator and CAML interactor; CVID; CVID2; TNFRSF14B; FLJ39942; MGC39952; MGC133214;
Gene ID: 23495
mRNA Refseq: NM_012452
Protein Refseq: NP_036584
MIM: 604907
UniProt ID: O14836
Chromosome Location: 17p11.2
Pathway: Cytokine-cytokine receptor interaction, organism-specific biosystem; Cytokine-cytokine receptor interaction, conserved biosystem; Intestinal immune network for IgA production, organism-specific biosystem; Intestinal immune network for IgA production, conserved biosystem; Primary immunodeficiency, organism-specific biosystem; Primary immunodeficiency, conserved biosystem; Syndecan-2-mediated signaling events, organism-specific biosystem;
Function: protein binding; receptor activity;

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