Recombinant Human TLR1, Fc-tagged, Biotinylated


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Recombinant Human TLR1, Fc-tagged, Biotinylated

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Cat.No. : TLR1-705H
Product Overview : The recombinant human TLR1-Fc fusion protein is expressed as a 778 amino acid protein consisting of Ser25 - Glu574 region of TLR1 (UniProt accession #Q15399) and a C-terminal Fc from human IgG1, which exists as a dimer under non-reducing conditions.
Source : Human cells
Species : Human
Tag : Fc
Form : Supplied at 0.5 mg/ml in sterile PBS pH7.4 (carrier & preservative free). The purified recombinant protein was labeled with Biotin (3-5 Biotin per molecule).
Bio-activity : Binds to the triacylated peptide biotinylated Pam3CysSerLys4 (PAM3CSK4).
Molecular Mass : Calculated molecular mass (kDa): 88.1; Estimated by SDS-PAGE under reducing condition (kDa): 90-100
Endotoxin : <0.1 eu per 1 μg of purified recombinant protein determined by the lal>
Purity : >90% judged by SDS-PAGE under reducing condition
Storage : The product is shipped at 4°C. Upon receipt, centrifuge the product briefly before opening the vial. It is recommended to store small aliquots at the temperature below –20°C for long-term storage and the product is stable for 3 months. The undiluted protein can be stored at 4°C for no more than 2 weeks. Avoid repeated freeze-thaw cycles.
Gene Name : TLR1 toll-like receptor 1 [ Homo sapiens ]
Official Symbol : TLR1
Synonyms : TLR1; toll-like receptor 1; CD281; KIAA0012; rsc786; toll/interleukin-1 receptor-like protein; TIL; TIL. LPRS5; MGC104956; MGC126311; MGC126312; DKFZp547I0610; DKFZp564I0682;
Gene ID : 7096
mRNA Refseq : NM_003263
Protein Refseq : NP_003254
MIM : 601194
UniProt ID : Q15399
Chromosome Location : 4p14
Pathway : Activated TLR4 signalling, organism-specific biosystem; Beta defensins, organism-specific biosystem; Defensins, organism-specific biosystem; Immune System, organism-specific biosystem; Innate Immune System, organism-specific biosystem; MyD88:Mal cascade initiated on plasma membrane, organism-specific biosystem; Toll Like Receptor 2 (TLR2) Cascade, organism-specific biosystem;
Function : lipopeptide binding; protein heterodimerization activity; receptor activity; transmembrane signaling receptor activity;
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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