Recombinant Human TLR1, Fc-tagged, Biotinylated TLR1-705H

Recombinant Human TLR1, Fc-tagged, Biotinylated

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Recombinant Human TLR1, Fc-tagged, Biotinylated

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Cat.No. : TLR1-705H
Product Overview : The recombinant human TLR1-Fc fusion protein is expressed as a 778 amino acid protein consisting of Ser25 - Glu574 region of TLR1 (UniProt accession #Q15399) and a C-terminal Fc from human IgG1, which exists as a dimer under non-reducing conditions.
Source : Human cells
Species : Human
Tag : Fc
Form : Supplied at 0.5 mg/ml in sterile PBS pH7.4 (carrier & preservative free). The purified recombinant protein was labeled with Biotin (3-5 Biotin per molecule).
Bio-activity : Binds to the triacylated peptide biotinylated Pam3CysSerLys4 (PAM3CSK4).
Molecular Mass : Calculated molecular mass (kDa): 88.1; Estimated by SDS-PAGE under reducing condition (kDa): 90-100
Endotoxin : <0.1 eu per 1 μg of purified recombinant protein determined by the lal>
Purity : >90% judged by SDS-PAGE under reducing condition
Storage : The product is shipped at 4°C. Upon receipt, centrifuge the product briefly before opening the vial. It is recommended to store small aliquots at the temperature below –20°C for long-term storage and the product is stable for 3 months. The undiluted protein can be stored at 4°C for no more than 2 weeks. Avoid repeated freeze-thaw cycles.
Gene Name : TLR1 toll-like receptor 1 [ Homo sapiens ]
Official Symbol : TLR1
Synonyms : TLR1; toll-like receptor 1; CD281; KIAA0012; rsc786; toll/interleukin-1 receptor-like protein; TIL; TIL. LPRS5; MGC104956; MGC126311; MGC126312; DKFZp547I0610; DKFZp564I0682;
Gene ID : 7096
mRNA Refseq : NM_003263
Protein Refseq : NP_003254
MIM : 601194
UniProt ID : Q15399
Chromosome Location : 4p14
Pathway : Activated TLR4 signalling, organism-specific biosystem; Beta defensins, organism-specific biosystem; Defensins, organism-specific biosystem; Immune System, organism-specific biosystem; Innate Immune System, organism-specific biosystem; MyD88:Mal cascade initiated on plasma membrane, organism-specific biosystem; Toll Like Receptor 2 (TLR2) Cascade, organism-specific biosystem;
Function : lipopeptide binding; protein heterodimerization activity; receptor activity; transmembrane signaling receptor activity;

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