Recombinant Human MARCKS protein, MYC/DDK-tagged
Cat.No. : | MARCKS-16H |
Product Overview : | Recombinant Human MARCKS fused with MYC/DDK tag at C-terminal was expressed in HEK293. |
- Specification
- Gene Information
- Related Products
Description : | The protein encoded by this gene is a substrate for protein kinase C. It is localized to the plasma membrane and is an actin filament crosslinking protein. Phosphorylation by protein kinase C or binding to calcium-calmodulin inhibits its association with actin and with the plasma membrane, leading to its presence in the cytoplasm. The protein is thought to be involved in cell motility, phagocytosis, membrane trafficking and mitogenesis. |
Source : | HEK293 |
Species : | Human |
Tag : | MYC/DDK |
Form : | 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
Molecular Mass : | 31.4 kDa |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Concentration : | >50 ug/mL as determined by microplate BCA method |
Gene Name : | MARCKS myristoylated alanine-rich protein kinase C substrate [ Homo sapiens ] |
Official Symbol : | MARCKS |
Synonyms : | MARCKS; myristoylated alanine-rich protein kinase C substrate; MACS, myristoylated alanine rich protein kinase C substrate (MARCKS, 80K L); myristoylated alanine-rich C-kinase substrate; 80K L; PKCSL; phosphomyristin; protein kinase C substrate, 80 kDa protein, light chain; myristoylated alanine-rich protein kinase C substrate (MARCKS, 80K-L); MACS; 80K-L; PRKCSL; FLJ14368; FLJ90045; |
Gene ID : | 4082 |
mRNA Refseq : | NM_002356 |
Protein Refseq : | NP_002347 |
MIM : | 177061 |
UniProt ID : | P29966 |
Chromosome Location : | 6q21 |
Pathway : | Fc gamma R-mediated phagocytosis, organism-specific biosystem; Fc gamma R-mediated phagocytosis, conserved biosystem; Integration of energy metabolism, organism-specific biosystem; Metabolism, organism-specific biosystem; Regulation of Insulin Secretion, organism-specific biosystem; Regulation of Insulin Secretion by Acetylcholine, organism-specific biosystem; |
Function : | actin filament binding; calmodulin binding; protein kinase C binding; |
Products Types
◆ Recombinant Protein | ||
MARCKS-1369H | Recombinant Human MARCKS Protein, His (Fc)-Avi-tagged | +Inquiry |
Marcks-3959M | Recombinant Mouse Marcks Protein, Myc/DDK-tagged | +Inquiry |
MARCKS-1097H | Recombinant Human MARCKS Protein, His&SUMO-tagged | +Inquiry |
MARCKS-5370M | Recombinant Mouse MARCKS Protein, His (Fc)-Avi-tagged | +Inquiry |
MARCKS-9563M | Recombinant Mouse MARCKS Protein | +Inquiry |
◆ Native Protein | ||
MARCKS-12B | Native Bovine MARCKS protein | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (5)
Ask a questionMARCKS is involved in synaptic function and may contribute to the synaptic dysfunction observed in Alzheimer's disease.
Yes, MARCKS is involved in inflammatory processes, and its dysregulation may contribute to inflammatory diseases.
Yes, MARCKS has been linked to neurological disorders, and its dysregulation may contribute to conditions such as Alzheimer's disease.
Yes, MARCKS is a potential target for drug development, particularly in conditions where its dysregulation contributes to disease progression.
Modulating MARCKS expression or activity may be considered as a therapeutic approach for certain cardiovascular conditions.
Customer Reviews (3)
Write a reviewMARCKS protein's ability to maintain structural integrity during imaging facilitates the detailed visualization of protein complexes and their interactions.
researchers have found MARCKS protein to be highly suitable for protein electron microscopy structure analysis.
MARCKS protein is highly recommended for research applications, particularly in ELISA assays and protein electron microscopy structure analysis.
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