"MARCKS" Related Products


Recombinant Human MARCKS protein, MYC/DDK-tagged

Cat.No.: MARCKS-16H
Product Overview: Recombinant Human MARCKS fused with MYC/DDK tag at C-terminal was expressed in HEK293.
Description: The protein encoded by this gene is a substrate for protein kinase C. It is localized to the plasma membrane and is an actin filament crosslinking protein. Phosphorylation by protein kinase C or binding to calcium-calmodulin inhibits its association with actin and with the plasma membrane, leading to its presence in the cytoplasm. The protein is thought to be involved in cell motility, phagocytosis, membrane trafficking and mitogenesis.
Source: HEK293
Species: Human
Form: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Mass: 31.4 kDa
Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration: >50 ug/mL as determined by microplate BCA method
Gene Name: MARCKS myristoylated alanine-rich protein kinase C substrate [ Homo sapiens ]
Official Symbol: MARCKS
Synonyms: MARCKS; myristoylated alanine-rich protein kinase C substrate; MACS, myristoylated alanine rich protein kinase C substrate (MARCKS, 80K L); myristoylated alanine-rich C-kinase substrate; 80K L; PKCSL; phosphomyristin; protein kinase C substrate, 80 kDa protein, light chain; myristoylated alanine-rich protein kinase C substrate (MARCKS, 80K-L); MACS; 80K-L; PRKCSL; FLJ14368; FLJ90045;
Gene ID: 4082
mRNA Refseq: NM_002356
Protein Refseq: NP_002347
MIM: 177061
UniProt ID: P29966
Chromosome Location: 6q21
Pathway: Fc gamma R-mediated phagocytosis, organism-specific biosystem; Fc gamma R-mediated phagocytosis, conserved biosystem; Integration of energy metabolism, organism-specific biosystem; Metabolism, organism-specific biosystem; Regulation of Insulin Secretion, organism-specific biosystem; Regulation of Insulin Secretion by Acetylcholine, organism-specific biosystem;
Function: actin filament binding; calmodulin binding; protein kinase C binding;

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