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Recombinant Human NLRP1 protein, MYC/DDK-tagged

Cat.No. : NLRP1-3804H
Product Overview : Recombinant Human NLRP1 fused with MYC/DDK tag at C-terminal was expressed in HEK293.
  • Specification
  • Gene Information
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Source : HEK293
Species : Human
Tag : MYC/DDK
Form : 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Mass : 165.7 kDa
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Notes : Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
Concentration : >50 ug/mL as determined by microplate BCA method
Publication :
A novel dual NLRP1 and NLRP3 inflammasome inhibitor for the treatment of inflammatory diseases (2022)
Gene Name : NLRP1 NLR family, pyrin domain containing 1 [ Homo sapiens ]
Official Symbol : NLRP1
Synonyms : NLRP1; NLR family, pyrin domain containing 1; NACHT, leucine rich repeat and PYD (pyrin domain) containing 1 , NALP1; NACHT, LRR and PYD domains-containing protein 1; CARD7; CLR17.1; DEFCAP; DKFZp586O1822; KIAA0926; NAC; nucleotide binding oligomerization domain; leucine rich repeat and pyrin domain containing 1; caspase recruitment domain protein 7; NACHT, LRR and PYD containing protein 1; NACHT, leucine rich repeat and PYD containing 1; caspase recruitment domain-containing protein 7; nucleotide-binding domain and caspase recruitment domain; death effector filament-forming Ced-4-like apoptosis protein; NACHT, leucine rich repeat and PYD (pyrin domain) containing 1; nucleotide-binding oligomerization domain, leucine rich repeat and pyrin domain containing 1; NALP1; SLEV1; PP1044; VAMAS1; DEFCAP-L/S;
Gene ID : 22861
mRNA Refseq : NM_033004
Protein Refseq : NP_127497
MIM : 606636
UniProt ID : Q9C000
Chromosome Location : 17p13
Pathway : Cellular roles of Anthrax toxin, organism-specific biosystem; Immune System, organism-specific biosystem; Inflammasomes, organism-specific biosystem; Innate Immune System, organism-specific biosystem; NOD-like receptor signaling pathway, organism-specific biosystem; NOD-like receptor signaling pathway, conserved biosystem; Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways, organism-specific biosystem;
Function : ATP binding; cysteine-type endopeptidase activator activity involved in apoptotic process; enzyme binding; nucleotide binding; protein binding; protein domain specific binding;

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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