Recombinant Human CASP9 protein


Home / Products / Recombinant Proteins / Recombinant Human CASP9 protein

Recombinant Human CASP9 protein

CASP9 Related Products

Price Inquiry

Welcome! For price inquiries, please feel free to contact us through the form below. We will get back to you as soon as possible.

Cat.No. : CASP9-49H
Product Overview : Recombinant Human CASP9 was expressed in E. coli.
Description : Caspase-9 is a member of the caspase-family of cysteine proteases. Similar to other caspases, caspase-9 also exists in cells as an inactive proenzyme. During the initiation of apoptosis procaspase-9 is processed at aspartate residues to form active caspase-9. As one of the initiator caspases, active caspase-9 functions to trigger activation of downstream effector caspases, leading to disassembly of cell structures.
Source : E. coli
Species : Human
Form : Lyophilized powder
Bio-activity : > 400 units/mg
Purity : ≥90%
Unit Definition : One unit of the recombinant caspase-9 is the enzyme activity that cleaves 1 nmol of the caspase substrate LEHD-pNA (pNA: pnitroanaline) per hour at 37 centigrade in a reaction solution containing 50 mM Hepes, pH 7.2, 50 mM NaCl, 0.1% Chaps, 10 mM EDTA, 5% Glycerol, and 10 mM DTT.
Applications : Active caspase-9 is useful in studying enzyme regulation, determining target substrates, screening caspase inhibitors, or as a positive control in caspase activity assays. We recommend using 1 unit/assay for analyzing caspase activity.
Notes : Centrifuge the vial prior to opening.
Storage : The lyophilized caspase-9 is stable for 1 year at –70 centigrade. Following reconstitution in PBS, the enzyme should be aliquoted and immediately stored at –70 centigrade. Avoid multiple freeze/thaw cycles as activity might decrease.
Reconstitution : Reconstitute to 1 unit per μl in PBS containing 15% glycerol.
Gene Name : CASP9 caspase 9, apoptosis-related cysteine peptidase [ Homo sapiens ]
Official Symbol : CASP9
Synonyms : CASP9; caspase 9, apoptosis-related cysteine peptidase; caspase 9, apoptosis related cysteine protease; caspase-9; APAF 3; ICE LAP6; MCH6; PPP1R56; protein phosphatase 1; regulatory subunit 56; apoptotic protease MCH-6; ICE-like apoptotic protease 6; apoptotic protease activating factor 3; protein phosphatase 1, regulatory subunit 56; APAF3; APAF-3; ICE-LAP6; CASPASE-9c;
Gene ID : 842
mRNA Refseq : NM_001229
Protein Refseq : NP_001220
MIM : 602234
UniProt ID : P55211
Chromosome Location : 1p36.21
Pathway : AKT phosphorylates targets in the cytosol, organism-specific biosystem; Activation of caspases through apoptosome-mediated cleavage, organism-specific biosystem; Adaptive Immune System, organism-specific biosystem; Alzheimers disease, organism-specific biosystem; Alzheimers disease, conserved biosystem; Amyotrophic lateral sclerosis (ALS), organism-specific biosystem; Amyotrophic lateral sclerosis (ALS), conserved biosystem;
Function : cysteine-type endopeptidase activity; enzyme activator activity; peptidase activity; protein binding;
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

Online Inquiry

  • Note: There will be extra charge for optional service!

Optional Service: Optional requirements on this protein

Other Requirements:

Apply For A Coupon

$50 OFF Your First Purchase

Apply For a Coupon

Enter your email here to subscribe.

creative biomart inc.

Easy access to products and services you need from our library via powerful searching tools.

Follow Us

Copyright © 2021 Creative BioMart. All Rights Reserved. Terms and Conditions | Privacy Policy