"IRF1" Related Products

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Recombinant Human IRF1 protein, MYC/DDK-tagged

Cat.No.: IRF1-128H
Product Overview: Recombinant Human IRF1 fused MYC/DDK tag at C-terminal was expressed in HEK293.
Description: IRF1 encodes interferon regulatory factor 1, a member of the interferon regulatory transcription factor (IRF) family. IRF1 serves as an activator of interferons alpha and beta transcription, and in mouse it has been shown to be required for double-stranded RNA induction of these genes. IRF1 also functions as a transcription activator of genes induced by interferons alpha, beta, and gamma. Further, IRF1 has been shown to play roles in regulating apoptosis and tumor-suppressoion.
Source: HEK293
Species: Human
Tag: MYC/DDK
Form: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Mass: 36.3 kDa
Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration: >50 ug/mL as determined by microplate BCA method
Gene Name: IRF1 interferon regulatory factor 1 [ Homo sapiens ]
Official Symbol: IRF1
Synonyms: IRF1; interferon regulatory factor 1; MAR; IRF-1;
Gene ID: 3659
mRNA Refseq: NM_002198
Protein Refseq: NP_002189
MIM: 147575
UniProt ID: P10914
Chromosome Location: 5q23-q31
Pathway: Apoptosis, organism-specific biosystem; Cytokine Signaling in Immune system, organism-specific biosystem; Factors involved in megakaryocyte development and platelet production, organism-specific biosystem; Glucocorticoid receptor regulatory network, organism-specific biosystem; Hemostasis, organism-specific biosystem; Hepatitis C, organism-specific biosystem; Hepatitis C, conserved biosystem;
Function: regulatory region DNA binding; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity;

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