"Casp6" Related Products

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Recombinant Mouse Casp6 protein, His-tagged

Cat.No.: Casp6-16M
Product Overview: Recombinant Mouse Casp6(6-162) fused with His tag was expressed in E. coli.
Description: This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein is processed by caspases 7, 8 and 10, and is thought to function as a downstream enzyme in the caspase activation cascade. Alternative splicing of this gene results in two transcript variants that encode different isoforms.
Source: E. coli
Species: Mouse
Tag: His
Form: Tris-based buffer,50% glycerol
AA Sequence: GFYKS REVFDPAEQY KMDHKRRGVA LIFNHERFFW HLTLPERRGT NADRDNLTRR FSDLGFEVKC FNDLRAEELL LKIHEVSTSS HIDADCFICV FLSHGEGNHV YAYDAKIEIQ TLTGLFKGDK CQSLVGKPKI FIIQACRGSQ HDVPVVPLDM VD
Purity: >90%
Notes: Repeated freezing and thawing is not recommended. Store working aliquots at 4 centigrade for up to one week.
Storage Buffer: Store at -20 centigrade, for extended storage, conserve at -20 centigrade or -80 centigrade.
Gene Name: Casp6 caspase 6 [ Mus musculus ]
Official Symbol: Casp6
Synonyms: CASP6; caspase 6; caspase-6; CASP-6; apoptotic protease Mch-2; Mch2; mCASP-6;
Gene ID: 12368
mRNA Refseq: NM_009811
Protein Refseq: NP_033941
MIM:
UniProt ID: O08738
Chromosome Location: 3; 3 H1
Pathway: Apoptosis, organism-specific biosystem; Apoptosis, organism-specific biosystem; Apoptosis, conserved biosystem; Apoptosis, organism-specific biosystem; Apoptosis Modulation by HSP70, organism-specific biosystem; Apoptosis signaling pathway, organism-specific biosystem; Apoptotic cleavage of cellular proteins, organism-specific biosystem;
Function: cysteine-type endopeptidase activity; cysteine-type peptidase activity; endopeptidase activity; hydrolase activity; peptidase activity; protein binding;

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