"HDAC6" Related Products

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Recombinant Human Histone Deacetylase 6, GST-tagged

Cat. No.: HDAC6-397H
Product Overview: Full Length Human HDAC6–Class IIb, 160kD with GST tag.
Description: Histone deacetylase 6, also known as HDAC6, is a human gene. Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class II of the histone deacetylase/acuc/apha family. It contains an internal duplication of two catalytic domains which appear to function independently of each other. This protein possesses histone deacetylase activity and represses transcription.
Source: HDAC6 was cloned from human heart cDNA and expressed in insect cells using a baculoviral expression system.
Purity: Purified, active enzyme.
Purification Procedure: Glutathione Column
Activity: 1000 units per vial. 1 unit is defined as the amount of enzyme that will convert 1picomole per minute per ug of protein at pH8 at 30°C.
Stability/Shelf-life: >6 months from date of shipment
Buffer Composition: 25mM Tris pH8, 120mM NaCl, 0.05% Tween-20 & 40% Glycerol.
Storage: –80°C
Gene Name: HDAC6 histone deacetylase 6 [ Homo sapiens ]
Synonyms: HDAC6; FLJ16239; HD6; JM21; histone deacetylase 6; OTTHUMP00000032398; EC 3.5.1.98; KIAA0901.
Gene ID: 10013
mRNA Refseq: NM_006044
Protein Refseq: NP_006035
MIM: 300272
UniProt ID: Q9UBN7
Chromosome Location: Xp11.23
Pathway: Gene Expression
Function: actin binding; histone deacetylase activity; histone deacetylase binding; hydrolase activity; metal ion binding; specific transcriptional repressor activity; tubulin deacetylase activity; zinc ion binding

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