Recombinant Full Length Rat HDAC6 Protein, C-His-tagged

• Cat.No.: HDAC6-23RFL
• Product Overview: Recombinant Full Length Rat HDAC6 Protein, fused to His-tag at C-terminus, was expressed in Baculovirus-Insect Cells.

Specification

• Description: Enables deacetylase activity. Involved in several processes, including generation of neurons; regulation of protein modification process; and response to glucocorticoid. Located in axon and centrosome. Used to study polycystic kidney disease and polycystic liver disease. Biomarker of hypertension and polycystic liver disease. Human ortholog(s) of this gene implicated in chondrodysplasia with platyspondyly, distinctive brachydactyly, hydrocephaly, and microphthalmia. Orthologous to human HDAC6 (histone deacetylase 6).
• Source: Insect cells
• Species: Rat
• Tag: C-His
• Form: Sterile 50mM Tris, 200mM NaCl, pH 8.0.
• Molecular Mass: 127 kDa
• AA Sequence: MTSTGQDSSTRQRKSRHNPQSPLQD SSATLKRGGKKGAVPHSSPNLAEVK KKGKMKKLSQPAEEDLIVGLQRLDL NSETRVPVGTGLVFDEQLNDFHCLW DDSFPENPERLHAIKEQLILEGLLG RCVSFQARFAEKEELMLVHSLEYID LMETTQYMNEGELRVLAGTYDSVYL HPNSYSCACLATGSVLRLVDAVMGA EIRNGMAVIRPPGHHAQRSLMDGYC MFNHLAVAARYAQKKHRIQRILIVD WDVHHGQGTQFIFDQDPSVLYFSIH RYEHGRFWPHLKASNWSTTGFGQGQ GYTINVPWNQVGMRDADYIAAFLHI LLPVAFEFQPQLVLVAAGFDALHGD PKGEMSATPAGFAHLTHFLMGLAGG KLILSLEGGYNLHALAKGVSGSLHT LLGDPCPMLESPVAPCASAQTSISC TLEALEPFWEVLERSVEPQDEDEVE GDMLEDEEEEGHWEATALPMDTWPL LQNRTGLVYDERMMSHCNLWDNHHP ETPQRILRIMCHLEEVGLAARCLIL PARPALDSELLTCHSAEYVERLRAT EKMKTRDLHREGANFESIYICPSTF ACAQLATGAACRLVEAVLSGEVLNG IAIVRPPGHHAEPDAACGFCFFNSV AVAARHAQVIAGRALRILIVDWDVH HGNGTQHIFEEDPSVLYVSLHRYDR GTFFPMGDEGASSQVGRAAGTGFTV NVPWNGPRMGDADYLATWHRLVLPI AYEFNPELVLISAGFDAAQGDPLGG CQVTPEGYAHLTHLLMGLAGGRIIL ILEGGYNLTSISESMAACTHSLLGD PPPQLTSLRPPQSGALASISEVIQV HRKYWRSLRLMKMEDKEERSSSRLV IKKLPQSASPVSAKGMTTPKGKVLE AGMRKPTAALPTKESTLGQAKAKTA KALLAQGQSSEQAAKGTTLDLATSK DTVGGATTDQCASVAATENSANQTT SGEEASGETESFGTSPSSNASKQTT GASPLHGAAAQQSPELGLSSTLELS SEAQEVQESEEGLLGEAAGGQDMNS LMLTQGFGDFNTQDVFYAVTPLSWC PHLMAVCPIPAAGLDVSQPCKTCGS FQENWVCLTCYQVYCSRYVNAHMVC HHEASEHPLVLSCVDLSTWCYLCQA YVHHEDLQDVKNAAHQNKFGEGMPH LQHHHHHHHHHH
• Purity: >90% by SDS-PAGE.
• Storage: Store it under sterile conditions at -20 to -80 centigrade. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
• Concentration: 0.27mg/ml by BCA.

Gene Information

• Gene Name: Hdac6 histone deacetylase 6 [ Rattus norvegicus (Norway rat) ]
• Official Symbol: HDAC6
• Synonyms: HDAC6; histone deacetylase 6; Hdac6
• Gene ID: 108348065
• mRNA Refseq: NM_001427028.1
• Protein Refseq: NP_001413957.1
• UniProt ID: D3ZVD8