"TFE3" Related Products


Recombinant Human TFE3

Cat. No.: TFE3-218H
Product Overview: Recombinant Human TFE-3 protein expressed inE.coliencodes 318-476 amino acids and has a molecular mass of 43 kDa.
Description: The DNA-binding factor TFE-3 contains adjacent helix-loop-helix (HLH) and leucine zipper (LZ) domains flanked by an upstream basic region. TFE-3 is ubiquitously expressed and can directly associates with DNA as either homodimers or heterodimers formed with two related proteins, TFEB or TFEC. TFE-3 binds to and activates the microE3 motif of the immunoglobulin heavy-chain enhancer to induce B-cell specific gene transcription and DNA recombination.
Source: Recombinant Human TFE-3 protein encloding 318-476 amino acids expressed inE. coli.
Formulation: Recombinant Human TFE-3 protein at 100µg/ml in 50mM Tris-Acetate, pH7.5, 1mM EDTA and 20% Glycerol.
Application And Suggested Dilutions: ELISA, Inhibition Assays, Western Blotting.
Characterization: On SDS-PAGE commassie blue stained gel, the purified recombinant protein shows a band at 43 kDa.
Storage & Stability: Store vial at -20°Cto -80°C. When stored at the recommended temperature, this protein is stable for 12 months.
Gene Name: TFE3 transcription factor binding to IGHM enhancer 3 [ Homo sapiens ]
Synonyms: TFE3; transcription factor binding to IGHM enhancer 3; TFEA; RCCP2; bHLHe33; transcription factor E family, member A; TFECL; hTFEC-L; bHLHe34; Protein TFE-C; Transcription factor EC-like; transcription factor EC; Transcription factor E3
Gene ID: 7030
mRNA Refseq: NM_006521
Protein Refseq: NP_006512
MIM: 314310
UniProt ID: P19532
Chromosome Location: Xp11.22
Function: promoter binding; protein binding; transcription factor activity

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Optional requirements on this protein    +Expand
C-fusion    N-fusion   Non-tagged
His    GST   Fc   Others
<1.0 eu/μg    <0.1 eu/μg   <0.01 eu/μg   Not required
Monomer Isolation    Dimer Isolation    Not required
>80% by SDS-PAGE    >90% by SDS-PAGE   >95% by SDS-PAGE   Others

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