||Recombinant Human C-reactive protein produced inE.Coliis a non-glycosylated polypeptide chain and has a total molecular mass of 115 kDa. The rHuCRP is purified by proprietary chromatographic techniques.
||CRP is an acute phase protein that correlates with inflammatory disease and is synthesized by hepatocytes during the acute phase response by certain cytokines (IL-1 and TNF Alpha and Beta). CRP levels increase dramatically (up to 1,000 fold) and serve as a useful marker of inflammation in such conditions as bacterial infection, rheumatoid arthritis, viral infections, transplantation rejection, meningitis, myocardial infarction, septicemia, osteomyelitis and others. CRP is also highly correlated to Serum Amyloid A levels.
||Sterile Filtered clear solution.
||The sterile protein solution) contains 20 mM Tris (ph 7.5), 2mM CaCl2, 0.14M NaCl and 0.05% NaN3.
||Greater than 95.0% as determined by: (a) Analysis by RP-HPLC. (b) Analysis by reducing and non-reducing SDS-PAGE Silver Stained.
||The rHuCRP should be stored at all times at 4°C.