Recombinant Human ATOX1 (Yeast) (Lyophilized)
Cat.No. : | ATOX1-451H |
Product Overview : | Recombinant Human full length HAH1 (Copper transport protein ATOX1, Metal transport protein ATX1) cloned from human cDNA with a C-terminal purification tag was expressed inE.coli.The protein consists of the human HAH1 (residues 1-68, swissprot O00244). The C-terminal tag is cleaved during purification. MW = 7.8 kDa. |
- Specification
- Gene Information
- Related Products
Cat. No. : | ATOX1-451H |
Description : | Copper transport protein ATOX1 is a protein that in humans is encoded by the ATOX1 gene. This gene encodes a copper chaperone that plays a role in copper homeostasis by binding and transporting cytosolic copper to ATPase proteins in the trans-Golgi network for later incorporation to the ceruloplasmin. This protein also functions as an antioxidant against superoxide and hydrogen peroxide, and therefore, may play a significant role in cancer carcinogenesis. Because of its cytogenetic location, this gene represents a candidate gene for 5q-syndrome. In melanocytic cells ATOX1 gene expression may be regulated by MITF. |
Source : | Escherichia Coli. |
Purity : | > 95% by SDS-PAGE. The protein was observed as a single band migrating at amolecular weight of (<10 kDa). |
Supplied As : | Lyophilized from a 1mg/ml solution containing 1mM DTT (1ml). The concentration is calculated from the absorbance at 280nm (e280= 2680 M-1 cm-1). |
Characteristics : | Under the above described conditions, to avoid precipitation or protein dimerization, the product can be concentrated to a maximum of 1mM. In case of precipitation, the precipitate can be partially redissolved using buffer solution with high conc. of DTT (20mM or more). |
Storage : | -20ºC. The protein is stable at 4ºC for at least 2 weeks and at 25ºC for at least several hours. After initial defrost, aliquot product into individual tubes and refreeze at -20ºC. Avoid repeated freeze/defrost cycles. |
Gene Name : | ATOX1 ATX1 antioxidant protein 1 homolog (yeast) [ Homo sapiens ] |
Synonyms : | ATOX1; ATX1 antioxidant protein 1 homolog (yeast); ATX1; HAH1; MGC138453; MGC138455; antioxidant protein 1; metal transport protein; copper transport protein; ATX1 (antioxidant protein 1, yeast) homolog 1; Copper transport protein ATOX1; Metal transport protein ATX1 |
Gene ID : | 475 |
mRNA Refseq : | NM_004045 |
Protein Refseq : | NP_004036 |
MIM : | 2270 |
UniProt ID : | O00244 |
Chromosome Location : | 5q32 |
Function : | copper chaperone activity; copper-dependent protein binding; metal ion binding |
Products Types
◆ Recombinant Protein | ||
ATOX1-506R | Recombinant Rat ATOX1 Protein, His (Fc)-Avi-tagged | +Inquiry |
ATOX1-840M | Recombinant Mouse ATOX1 Protein, His (Fc)-Avi-tagged | +Inquiry |
ATOX1-699H | Recombinant Human ATOX1 protein, His-tagged | +Inquiry |
ATOX1-8172Z | Recombinant Zebrafish ATOX1 | +Inquiry |
ATOX1-2741H | Recombinant Human Antioxidant Protein 1 Homolog (Yeast) | +Inquiry |
◆ Lysates | ||
ATOX1-8616HCL | Recombinant Human ATOX1 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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