Cat. No. :	TAC3-79H
Product Overview :	Recombinant human Neurokinin B, fused to His-tag at N-terminus, was expressed inE.coliand purified by using conventional chromatography. MW =13.8 kDa (125aa).
Description :	Neurokinin B, a member of the substance P-related tachykinin family, was previously known to be present in the same hypothalamic neurons as kisspeptin. This protein and its receptor are critical switches of regulator of human puberty, governed by the brain through the release of the hormone GnRH (gonadotropin-releasing hormone) which starts a series of processes that ultimately leads to the production of sex hormones. Many studies suggest new approaches to the pharmacological control of human reproduction and sex hormone-related diseases.
Source :	E.coli.
Amino Acid Sequence :	MGSSHHHHHH SSGLVPRGSH QSFGAVCKEP QEEVVPGGGR SKRDPDLYQL LQRLFKSHSS LEGLLKALSQ ASTDPKESTS PEKRDMHDFF VGLMGKRSVQ PDSPTDVNQE NVPSFGILKY PPRAE.
Form :	Liquid. In 20 mM Tris-HCl buffer (pH 8.0) containing 20% glycerol.
Purity :	> 95% by SDS – PAGE.
Concentration :	0.5 mg/ml (determined by Bradford assay).
Storage :	Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.

Gene Name :	TAC3 tachykinin 3 [ Homo sapiens ]
Synonyms :	TAC3; tachykinin 3; NKB; NKNB; PRO1155; ZNEUROK1; neurokinin beta; OTTHUMP00000211130; gamma tachykinin 3; preprotachykinin B; neurokinin-B protein; neurokinin B-like protein; neuromedin K; neurokinin beta; Tachykinin-3; Neuromedin-K; UNQ585/PRO1155; neuromedin K; neuromedin K, neurokinin beta
Gene ID :	6866
mRNA Refseq :	NM_013251
Protein Refseq :	NP_037383
MIM :	162330
UniProt ID :	Q9UHF0
Chromosome Location :	12q13-q21
Pathway :	Neuroactive ligand-receptor interaction; Signaling by GPCR
Function :	receptor binding

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