"UBE2L3" Related Products

Expand
Expand

Recombinant Human Ubiquitin-conjugating Enzyme E2L 3

Cat. No. : UBE2L3-33H
Product Overview : Recombinant Human UbcH7(154amino acid) was over-expressed inE.coliand purified by using conventional chromatography techniques. MW = 17.9 kDa (154 aa).
Description : Human Ubquitin-conjugating enzyme 7(UbcH7) is a ubiquitin-conjugating enzyme (E2) mediating c-fos degradation, transcription factor NF-B maturation, and human papilloma virus-mediated p53 and Myc protein degradation, in vitro. The ubiquitin-conjugating enzymes(E2s) are essential components of the post-translational protein ubiquitination pathway, mediating the transfer of activated ubiquitin to substrate proteins. The human UBE2L1-UBE2L4 gene could potentially encode different isoforms of the UbcH7. UBE2L3 gene, located at chromosome 22q11.2, is the only identical family member with introns and encodes a polypeptide sequence identical to that of UbcH7.
Source : E.coli.
Amino Acid Sequence : MAASRRLMKE LEEIRKCGMK NFRNIQVDEA NLLTWQGLIV PDNPPYDKGA FRIEINFPAE YPFKPPKITF KTKIYHPNID EKGQVCLPVI SAENWKPATK TDQVIQSLIA LVNDPQPEHP LRADLAEEYS KDRKKFCKNA EEFTKKYGEK RPVD
Form : Liquid. In 50 mM HEPES (pH 7.5) containing 150 mM NaCl 1 mM DTT and 10% glycerol.
Purity : > 95% by SDS – PAGE.
Concentration : 1 mg/ml (determined by Bradford assay).
Storage : Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
Gene Name : UBE2L3 ubiquitin-conjugating enzyme E2L 3 [ Homo sapiens ]
Synonyms : E2-F1; L-UBC; UBCH7; UbcM4; ubiquitin-conjugating enzyme E2L 3; UB2L3_HUMAN; EC 6.3.2.19; Ubiquitin-protein ligase L3;Ubiquitin carrier protein L3; UBCE7; ubiquitin carrier protein; ubiquitin-conjugating enzyme E2L3; ubiquitin-conjugating enzyme UBCH7; ubiquitin-protein ligase; UBE2L3
Gene ID : 7332
mRNA Refseq : NM_003347
Protein Refseq : NP_003338
MIM : 603721
UniProt ID : P68036
Chromosome Location : 22q11.21
Pathway : Parkinson"s disease
Function : enzyme binding; ligase activity; small conjugating protein ligase activity; ubiquitin-protein ligase activity

Online Inquiry

Note: There will be extra charge for optional service!

Please input "biomart" as verification code. Please review Creative BioMart's privacy policy for more information

Optional requirements on this protein    +Expand

Price Inquiry

Welcome! For price inquiries, please feel free to contact us through the form below. We will get back to you as soon as possible.