Recombinant Human Ubiquitin-conjugating Enzyme E2I
Cat.No. : | UBE2I-34H |
Product Overview : | Recombinant Human Ubiquitin-conjugating enzyme E2I was expressed inE.coli. MW =18 kDa (158 aa). |
- Specification
- Gene Information
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Cat. No. : | UBE2I-34H |
Description : | Human Ubc9 is homologous to ubiquitin-conjugating enzymes (E2s). However, instead of conjugating ubiquitin, it conjugates an ubiquitin homologue, small ubiquitin-like modifier 1(SUMO-1). And hUbc9 retains striking structural and functional conservation with yeast Ubc9. The ubiquitin-dependent protein degradation system has been recognized as a complete enzymatic pathway that is responsible for the selective degradation of abnormal and short-lived proteins. The conjugation of ubiquitin requires the activities of ubiquitin-activating (E1) and –conjugating (E2) enzymes. |
Source : | E.coli. |
Amino Acid Sequence : | MSGIALSRLA QERKAWRKDH PFGFVAVPTK NPDGTMNLMN WECAIPGKKG TPWEGGLFKL RMLFKDDYPS SPPKCKFEPP LFHPNVYPSG TVCLSILEED KDWRPAITIK QILLGIQELL NEPNIQDPAQ AEAYTIYCQN RVEYEKRVRA QAKKFAPS |
Form : | Liquid. In 50 mM HEPES (pH 7.5) containing 1 mM DTT, 150 mM NaCl 10% glycerol. |
Purity : | > 95% by SDS – PAGE. |
Concentration : | 1 mg/ml (determined by Bradford assay). |
Endotoxin Level : | < 1.0 EU per 1 μg of protein (determined by LAL method). |
Storage : | Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles. |
Gene Name : | UBE2Iubiquitin-conjugating enzyme E2I (UBC9 homolog, yeast) [Homo sapiens] |
Synonyms : | P18; UBC9; C358B7.1; ubiquitin-conjugating enzyme E2I (UBC9 homolog, yeast); ubiquitin-conjugating enzyme E2I (homologous to yeast UBC9); UBC9_HUMAN; SUMO-conjugating enzyme UBC9; EC 6.3.2.-; SUMO-protein ligase; Ubiquitin-protein ligase I; Ubiquitin carrier protein I; Ubiquitin carrier protein 9; UBE2I;UBCE9; Ubiquitin-protein ligase I; ubiquitin carrier protein; ubiquitin conjugating enzyme 9; ubiquitin-conjugating enzyme E2I; ubiquitin-conjugating enzyme UbcE2A; ubiquitin-like protein SUMO-1 conjugating enzyme |
Gene ID : | 7329 |
mRNA Refseq : | NM_003345 |
Protein Refseq : | NP_003336 |
MIM : | 601661 |
UniProt ID : | P63279 |
Chromosome Location : | 16p13.3 |
Function : | HLH domain binding;ligase activity;protein binding; small conjugating protein ligase activity |
Products Types
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UBE2I-0010H | Recombinant Human UBE2I Protein (S2-S158), His/Strep tagged | +Inquiry |
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UBE2I-0009H | Recombinant Human UBE2I Protein (S2-S158), Tag Free | +Inquiry |
◆ Lysates | ||
UBE2I-574HCL | Recombinant Human UBE2I 293 Cell Lysate | +Inquiry |
UBE2I-573HCL | Recombinant Human UBE2I 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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