Recombinant Human CEACAM6 protein, His-tagged
Cat.No. : | CEACAM6-664H |
Product Overview : | Recombinant Human CEACAM6 (Lys35-Gly320) protein was fused to His-tag at C-terminus and expressed in human 293 cells (HEK293). |
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Description : | Carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) (CEACAM6) is also known as CD66c (Cluster of Differentiation 66c), CEAL, NCA, and is one of seven human CEACAM family members within the immunoglobulin superfamily. In humans, CEACAMs include type I transmembrane proteins (CEACAM1, CEACAM3, and CEACAM4) and GPI-linked molecules (CEACAM5 through CEACAM8). There is no human CEACAM2. CEACAM 6 contains one N-terminal V-type Ig-like domain (N domain), followed by two C2-type Ig-like domains. It shows considerable glycosylation, including (sialyl) LewisX, which mediates binding to E-selectin, galectins and some bacterial fimbrae. CEACAM-6 is expressed by granulocytes and their progenitors. It is also expressed by epithelia of various organs and is upregulated in pancreatic and colon adenocarcinomas, as well as hyperplastic polyps. Resistance to adhesion-related apoptosis in tumor cells is conferred in the condition of CEACAM6 overexpression. |
Source : | HEK293 |
Species : | Human |
Tag : | His |
Predicted N Terminal : | Lys35 |
Form : | Lyophilized from 0.22 μm filtered solution in PBS, pH7.4, 10% trehalose. |
Molecular Mass : | The protein has a calculated MW of 32.0 kDa. The protein migrates as 45-65 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation. |
Protein length : | Lys35-Gly320 |
Endotoxin : | Less than 1.0 EU per μg by the LAL method. |
Purity : | >95% as determined by SDS-PAGE. |
Storage : | For long term storage, the product should be stored at lyophilized state at -20 centigrade or lower. Please avoid repeated freeze-thaw cycles. This product is stable after storage at: -20 to -70 centigrade for 12 months in lyophilized state; -70 centigrade for 3 months under sterile conditions after reconstitution. |
Reconstitution : | It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4℃ before opening to recover the entire contents. |
Gene Name : | CEACAM6 |
Official Symbol : | CEACAM6 |
Synonyms : | CEACAM6; carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen); NCA; carcinoembryonic antigen-related cell adhesion molecule 6; CD66c; normal cross-reacting antigen; non-specific crossreacting antigen; CEAL |
Gene ID : | 4680 |
mRNA Refseq : | NM_002483 |
Protein Refseq : | NP_002474 |
MIM : | 163980 |
UniProt ID : | P40199 |
Products Types
◆ Recombinant Protein | ||
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CEACAM6-3191H | Recombinant Human CEACAM6 Protein, His-tagged | +Inquiry |
CEACAM6-1096H | Recombinant Human CEACAM6 Protein, GST-Tagged | +Inquiry |
CEACAM6-179H | Recombinant Human CEACAM6 Protein, His-tagged | +Inquiry |
CEACAM6-335H | Active Recombinant Human CEACAM6 Protein, His & Avi-tagged, Biotinylated | +Inquiry |
◆ Lysates | ||
CEACAM6-2797HCL | Recombinant Human CEACAM6 cell lysate | +Inquiry |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (5)
Ask a questionCEACAM6 is involved in regulating the inflammatory response in the gut, making it relevant to inflammatory bowel disease.
CEACAM6 levels can be measured in clinical tests to assess inflammation in the gastrointestinal tract.
Yes, CEACAM6 levels can be monitored to track the progression of certain diseases.
Research is ongoing to develop therapies that inhibit CEACAM6 interactions with pathogens to prevent infection.
Some immunotherapeutic approaches involve targeting CEACAM6 to enhance the immune response against cancer cells.
Customer Reviews (3)
Write a reviewThey provide a wealth of technical information and extensive documentation about the CEACAM6 protein, ensuring I have a comprehensive understanding of its characteristics, handling protocols, and storage requirements.
the manufacturer ensures a streamlined supply chain management system to meet my trial's requirements.
the manufacturer facilitates access to the latest scientific advancements and developments related to CEACAM6 protein research.
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