Active Recombinant Human DLL4 protein, Fc-tagged
Cat.No. : | DLL4-686H |
Product Overview : | Recombinant Human DLL4 protein(Ser 27 - Pro 524), fused with Fc tag, was expressed in HEK293. |
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Source : | HEK293 |
Species : | Human |
Tag : | Fc |
Form : | Lyophilized from 0.22 μm filtered solution in Tris with Glycine, Arginine and NaCl, pH7.5 with trehalose as protectant. |
Bio-activity : | Immobilized Human DLL4, Fc Tag at 1 μg/mL (100 μL/well) can bind Monoclonal Anti-Human DLL4 Antibody, Human IgG1 with a linear range of 1-16 ng/mL.Immobilized Mouse NOTCH1, His Tag at 2 μg/mL (100 μL/well) can bind Human DLL4, Fc Tag with a linear range of 0.5-8 ng/mL. |
Molecular Mass : | This protein carries a human IgG1 Fc tag at the C-terminusThe protein has a calculated MW of 80.9 kDa. The protein migrates as 90-110 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation. |
Proteinlength : | Ser27-Pro524 |
Endotoxin : | Less than 1.0 EU per μg by the LAL method. |
Purity : | >95% as determined by SDS-PAGE. |
Storage : | For long term, the product should be stored at lyophilized state at -20°C or lower.Please avoid repeated freeze-thaw cycles. This product is stable after at: -20°C to -70°C for 12 months in lyophilized state; -70°C for 3 months under sterile conditions after reconstitution. |
Reconstitution : | It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4°C before opening to recover the entire contents. |
Gene Name : | DLL4 delta-like 4 (Drosophila) [ Homo sapiens ] |
Official Symbol : | DLL4 |
Synonyms : | DLL4; delta-like 4 (Drosophila); delta like 4 homolog (Drosophila); delta-like protein 4; delta4; delta 4; delta ligand 4; notch ligand DLL4; delta-like 4 homolog; delta-like 4 protein; notch ligand delta-2; drosophila Delta homolog 4; hdelta2; MGC126344; |
Gene ID : | 54567 |
mRNA Refseq : | NM_019074 |
Protein Refseq : | NP_061947 |
MIM : | 605185 |
UniProt ID : | Q9NR61 |
Products Types
◆ Recombinant Protein | ||
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Dll4-2402M | Recombinant Mouse Dll4 Protein, His (Fc)-Avi-tagged | +Inquiry |
DLL4-201H | Recombinant Human DLL4 Protein, His-tagged | +Inquiry |
DLL4-202H | Recombinant Human DLL4 Protein, Fc-tagged | +Inquiry |
DLL4-1349H | Recombinant Human DLL4 Protein, His&GST-tagged | +Inquiry |
◆ Lysates | ||
DLL4-2495MCL | Recombinant Mouse DLL4 cell lysate | +Inquiry |
DLL4-2507HCL | Recombinant Human DLL4 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (5)
Ask a questionDLL4 is implicated in the regulation of vascular inflammation and plaque formation, making it a potential target for atherosclerosis treatments.
DLL4 has been linked to Alzheimer's disease as it can influence amyloid-beta accumulation and the activation of microglia in the brain.
DLL4 levels can serve as a potential biomarker in some diseases, such as certain cancers, where it may indicate disease progression.
Challenges include potential side effects, the need for personalized treatment approaches, and the complexity of the Notch signaling pathway.
DLL4 can modulate tissue regeneration by influencing stem cell behavior and promoting tissue repair processes.
Customer Reviews (3)
Write a reviewThey ensure a consistent and reliable supply of DLL4 protein, minimizing any potential disruptions in my experimental workflow.
the manufacturer's commitment to scientific collaboration and knowledge sharing greatly enhances my research experience.
This collaborative approach empowers me to integrate cutting-edge knowledge, explore innovative techniques, and expand the impact of my research.
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