Serum Albumin

• Cat.No.: CBCRY36

Specification

• Cat. No.: CBCRY36
• Background: 3"-Azido-3"-deoxythymidine (AZT) is the first clinically effective drug for the treatment of human immunodeficiency virus infection. The drug interaction with human serum albumin (HSA) has been an important component in understanding its mechanism of action, especially in drug distribution and in drug-drug interaction on HSA in the case of multi-drug therapy.
• Protein Classification: Lipid binding protein
• Structure Weight: 68485.53 Da
• Polymer: 1
• Molecule: Serum albumin
• Chain Length: 585 amino acids
• PDB ID: 3B9M
• MMDB ID: 64671
• Source: E.coli
• Method: X-Ray Diffraction
• Resolution: 2.70Å
• Ligand Chemical Component: AZZ; Myristic acid; 2-hydroxybenzoic acid
• Reference: Zhu, L., Yang, F., Chen, L., Meehan, E.J., Huang, M. (2008) A new drug binding subsite on human serum albumin and drug-drug interaction studied by X-ray crystallography J.Struct.Biol. 162: 40-49

Gene Information

• Gene Name: ALB
• Synonyms: DKFZp779N1935; PRO0883; PRO0903; PRO1341; cell growth inhibiting protein 42; growth-inhibiting protein 20; serum albumin
• UniProt ID: P02768
• Gene ID: 213
• Chromosome Location: 4q11-q13
• Function: DNA binding; fatty acid binding; copper ion binding; protein binding; drug binding; lipid binding; toxin binding; antioxidant activity; oxygen binding; pyridoxal phosphate binding; metal ion binding