Recombinant Human Apolipoprotein D, GST-tagged APOD-1321H

Recombinant Human Apolipoprotein D, GST-tagged


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Recombinant Human Apolipoprotein D, GST-tagged

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Cat. No. : APOD-1321H
Product Overview : Recombinant Human APOD full length protein expressed inE.colishows a 48 kDa band on SDS-PAGE. The APO-D is purified by proprietary chromatographic techniques.
Description : Apolipoprotein-D is mainly associated with high density lipoproteins in human plasma. Apolipoprotein-D is an atypical apolipoprotein and, based on its primary structure, Apolipoprotein-D is a member of the lipocalin family. Lipocalins adopt a beta-barrel tertiary structure and transport small hydrophobic ligands. Apolipoprotein-D binds cholesterol, progesterone, pregnenolone, bilirubin and arachidonic acid. Apolipoprotein-D is expressed in numerous tissues having high levels of expression in spleen, testes and brain. Apolipoprotein-D is present at high concentrations in the cyst fluid of women with gross cystic disease of the breast, a condition associated with increased risk of breast cancer. Apolipoprotein-D accumulates in regenerating peripheral nerves and in the cerebrospinal fluid of patients with neurodegenerative conditions, such as Alzheimer"s disease. Apolipoprotein-D participates in maintenance and repair within the central and peripheral nervous systems. Apolipoprotein-D is a multi-ligand, multi-functional transporter and transports a ligand from 1 cell to another within an organ, scavenge a ligand within an organ for transport to the blood or could transport a ligand from the circulation to specific cells within a tissue.
Source : Escherichia Coli.
Physical Appearance : Sterile Filtered clear solution.
Formulation : APO-D protein at 100µg/ml in 50mM Tris-Acetate, pH7.5, 1mM EDTA and 20% Glycerol.
Applications : ELISA, Inhibition Assays, Western Blotting.
Stability : Store vial at -20℃ to -80℃. When stored at the recommended temperature, this protein is stable for 12 months.
Gene Name : APOD apolipoprotein D [ Homo sapiens ]
Synonyms : Apolipoprotein D; Apo-D; ApoD; APOD
Gene ID : 347
mRNA Refseq : NM_001647
Protein Refseq : NP_001638
MIM : 107740
UniProt ID : P05090
Chromosome Location : 3q26.2-qter
Function : lipid binding; transporter activity; lipid transporter activity; protein binding; retinoid binding

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