Recombinant Human CDK7/CCNH/MNAT1, His-tagged, Active
Cat.No. : | CDK7/CCNH/MNAT1-279H |
Product Overview : | Recombinant human full-length CDK7, Cyclin H1 and MNATI were co-expressed by baculovirus inSf9insect cells using N-terminal His tags. MW=40kDa, Cyclin H1 ~39kDa, and MNAT1 ~37kDa. |
- Specification
- Gene Information
- Related Products
Cat. No. : | CDK7/CCNH/MNAT1-279H |
Description : | CDK7 gene is a member of the cyclin-dependent protein kinase family that is important regulators of cell cycle progression. CDK7 forms a trimeric complex with cyclin H and MAT1, which functions as a CDK-activating kinase (CAK). CDK7 is an essential component of the transcription factor TFIIH that is involved in transcription initiation and DNA repair. CDK7 is thought to serve as a direct link between the regulation of transcription and the cell cycle. |
Source : | Sf9 insect cells using baculovirus. |
Sequence : | Full-length. |
Applications : | Kinase Assay, Western Blot. |
Storage And Stability : | Store product at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles. |
Gene Name : | CDK7 cyclin-dependent kinase 7 [ Homo sapiens ],CCNH cyclin H [ Homo sapiens ],MNAT1 menage a trois homolog 1, cyclin H assembly factor (Xenopus laevis) [ Homo sapiens ] |
Synonyms : | CDK7; cyclin-dependent kinase 7; CAK1; MO15; STK1; CDKN7; p39MO15; cyclin-dependent kinase 7 (homolog of Xenopus MO15 cdk-activating kinase); cyclin-dependent kinase 7 (MO15 homolog, Xenopus laevis, cdk-activating kinase);Cell division protein kinase 7;EC2.7.11.22;EC2.7.11.23; CDK-activating kinase; TFIIH basal transcription factor complex kinase subunit; 39 kDa protein kinase; P39 Mo15; CCNH; cyclin H; CAK; p34; p37; CDK-activating kinase; cyclin-dependent kinase-activating kinase; MO15-associated protein; Cyclin-H; MNAT1; menage a trois homolog 1, cyclin H assembly factor (Xenopus laevis); MAT1; TFB3; RNF66; menage a trois 1 (CAK assembly factor); CDK-activating kinase assembly factor MAT1; CDK7/cyclin H assembly factor;p35; p36; RING finger protein 66; Cyclin G1-interacting protein |
Gene ID : | 1022,902,4331 |
mRNA Refseq : | NM_001799,NM_001239,NM_002431 |
Protein Refseq : | NP_001790,NP_001230,NP_002422 |
UniProt ID : | P50613, P51946, P51948 |
Chromosome Location : | 5q12.1, 5q13.3-q14, 14q23 |
MIM : | 601955,601953,602659 |
Pathway : | Cell cycle; Cell Cycle, Mitotic; Nucleotide excision repair; DNA Repair; Gene Expression; HIV Infection; Transcription; mRNA Processing |
Function : | ATP binding; DNA-dependent ATPase activity ; RNA polymerase II carboxy-terminal domain kinase activity ; androgen receptor binding; protein C-terminus binding; transcription coactivator activity; cyclin-dependent protein kinase activity; nucleotide binding; transferase activity; protein N-terminus binding; zinc ion binding |
Products Types
◆ Recombinant Protein | ||
CDK7-1036H | Active Recombinant Human CDK7 Protein, GST-Tagged | +Inquiry |
Cdk7-868M | Recombinant Mouse Cdk7 Protein, MYC/DDK-tagged | +Inquiry |
CDK7-566H | Recombinant Human CDK7 Protein, His (Fc)-Avi-tagged | +Inquiry |
CDK7-615R | Recombinant Rhesus Macaque CDK7 Protein, His (Fc)-Avi-tagged | +Inquiry |
CDK7-1033H | Recombinant Human CDK7 Protein, GST-Tagged | +Inquiry |
◆ Lysates | ||
CDK7-7621HCL | Recombinant Human CDK7 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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