"PRKACB" Related Products


Recombinant Human PRKACB, GST-tagged, Active

Cat. No. : PRKACB-395H
Product Overview : Recombinant human full-length PKAcbeta was expressed by baculovirus inSf9 cellsusing an N-terminal GST tag. MW=65 kDa.
Description : The catalytic subunit C-beta of PKA (PKAcβ) is a member of the Ser/Thr protein kinase family (the PKA catalytic subunit consist of three gene products: C-alpha, C-beta, and C-gamma) and has been assigned to human chromosome region 1p36.1. PKAcβ is derived from a gene distinct from C-alpha and shows tissue-specific expression. At the amino acid level C-alpha and C-beta showed 93% homology.
Source : Sf9 insect cells using baculovirus.
Sequence : Full-length.
Applications : Kinase Assay, Western Blot.
Storage And Stability : Store product at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
Gene Name : PRKACB protein kinase, cAMP-dependent, catalytic, beta [ Homo sapiens ]
Synonyms : PRKACB; protein kinase, cAMP-dependent, catalytic, beta; PKACB; MGC9320; MGC41879; DKFZp781I2452; PKACb; cAMP-dependent protein kinase catalytic subunit beta; EC; PKA C-beta
Gene ID : 5567
mRNA Refseq : NM_002731
Protein Refseq : NP_002722
UniProt ID : P22694
Chromosome Location : 1p36.1
MIM : 176892
Pathway : Apoptosis; Calcium signaling pathway; Chemokine signaling pathway; Dilated cardiomyopathy; Gap junction; GnRH signaling pathway; Hedgehog signaling pathway; Insulin signaling pathway; Melanogenesis; Long-term potentiation; Progesterone-mediated oocyte maturation; Wnt signaling pathway; Vibrio cholerae infection
Function : ATP binding; nucleotide binding; transferase activity; cAMP-dependent protein kinase activity; cAMP-dependent protein kinase inhibitor activity; protein serine/threonine kinase activity; protein kinase binding

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