||Recombinant Human Full length HAH1 cloned from human cDNA, is expressed inE. coli.
||Copper transport protein ATOX1 is a protein that in humans is encoded by the ATOX1 gene. This gene encodes a copper chaperone that plays a role in copper homeostasis by binding and transporting cytosolic copper to ATPase proteins in the trans-Golgi network for later incorporation to the ceruloplasmin. This protein also functions as an antioxidant against superoxide and hydrogen peroxide, and therefore, may play a significant role in cancer carcinogenesis. Because of its cytogenetic location, this gene represents a candidate gene for 5q-syndrome. In melanocytic cells ATOX1 gene expression may be regulated by MITF.
||> 95% by SDS-PAGE. The protein was observed as a single band migrating at a molecular weight <10 kDa.
||Under the above described conditions, to avoid precipitation or protein dimerization, the product can be concentrated to a maximum of 1mM.
||-20oC. The protein is stable at 4oC for at least 2 weeks and at 25oC for at least several hours. After initial defrost, aliquot product into individual tubes and refreeze at -20oC. Avoid repeated freeze/defrost cycles.