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Recombinant Human Antioxidant Protein 1 Homolog (Yeast)

Cat. No.: ATOX1-2741H
Product Overview: Recombinant Human Full length HAH1 cloned from human cDNA, is expressed inE. coli.
Description: Copper transport protein ATOX1 is a protein that in humans is encoded by the ATOX1 gene. This gene encodes a copper chaperone that plays a role in copper homeostasis by binding and transporting cytosolic copper to ATPase proteins in the trans-Golgi network for later incorporation to the ceruloplasmin. This protein also functions as an antioxidant against superoxide and hydrogen peroxide, and therefore, may play a significant role in cancer carcinogenesis. Because of its cytogenetic location, this gene represents a candidate gene for 5q-syndrome. In melanocytic cells ATOX1 gene expression may be regulated by MITF.
Source: E. coli.
Purity: > 95% by SDS-PAGE. The protein was observed as a single band migrating at a molecular weight <10 kDa.
Characteristics: Under the above described conditions, to avoid precipitation or protein dimerization, the product can be concentrated to a maximum of 1mM.
Storage: -20oC. The protein is stable at 4oC for at least 2 weeks and at 25oC for at least several hours. After initial defrost, aliquot product into individual tubes and refreeze at -20oC. Avoid repeated freeze/defrost cycles.
Gene Name: ATOX1 ATX1 antioxidant protein 1 homolog (yeast) [ Homo sapiens ]
Synonyms:
ATOX1; ATX1 antioxidant protein 1 homolog (yeast); ATX1; HAH1; MGC138453; MGC138455; antioxidant protein 1; metal transport protein; copper transport protein; ATX1 (antioxidant protein 1, yeast) homolog 1; Copper transport protein ATOX1; Metal transport protein ATX1
Gene ID: 475
mRNA Refseq: NM_004045
Protein Refseq: NP_004036
MIM: 2270
UniProt ID: O00244
Chromosome Location: 5q32
Function: copper chaperone activity; copper-dependent protein binding; metal ion binding

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