Recombinant Human RPS6KA6, GST-tagged, Active RPS6KA6-427H

Recombinant Human RPS6KA6, GST-tagged, Active

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Recombinant Human RPS6KA6, GST-tagged, Active

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Cat. No. : RPS6KA6-427H
Product Overview : Recombinant full-length human RPS6KA6 was expressed bybaculovirusinSf9 insect cellsusing an N-terminal GST tag. MW=112kDa.
Description : RSK4 is a member of the 90-kDa ribosomal S6 kinase family which are important components of growth factor mediated stimulation of cellular proliferation, survival and differentiation. RSK4 is activated via coordinated phosphorylation by ERK and 3-phosphoinositide-dependent protein kinase-1 (PDK1). RSK4 is often associated with contiguous gene syndromes consisting of X-linked deafness type 3 (DFN3), mental retardation (MRX) and choroideremia (CHM). RSK4 is most abundantly expressed in the brain and kidney.
Source : Sf9 insect cells using baculovirus.
Sequence : Full-lengt h.
Applications : Kinase Assay, Western Blot.
Storage And Stability : Store product at –70oC. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
nullValue_other : Long-term potentiation; MAPK signaling pathway; Neurotrophin signaling pathway; Progesterone-mediated oocyte maturation; mTOR signaling pathway; Signalling by NGF
Gene Name : RPS6KA6 ribosomal protein S6 kinase, 90kDa, polypeptide 6 [ Homo sapiens ]
Synonyms : RPS6KA6; ribosomal protein S6 kinase, 90kDa, polypeptide 6; RSK4; PP90RSK4; S6K-alpha 6; ribosomal S6 kinase 4; EC 2.7.11.1
Gene ID : 27330
mRNA Refseq : NM_014496
Protein Refseq : NP_055311
MIM : 300303
UniProt ID : Q9UK32
Chromosome Location : Xq21
Function : ATP binding; magnesium ion binding; nucleotide binding; protein binding; transferase activity; protein serine/threonine kinase activity
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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