"PTPN2" Related Products

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Recombinant Human PTPN2,GST-tagged,Active

Cat. No. : PTPN2-464H
Product Overview : Recombinant human full length PTPN2 was expressed inE.colicells using a N-terminal GST tag. MW=69kDa.
Description : Protein tyrosine phosphatase, non-receptor type 2 (PTPN2), is one of the most abundant mammalian tyrosine phosphatase. The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. By virtue of protein tyrosine phosphatase activity, PTPN2 is known to be a signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation involved in cell communication and signal transduction.
Source : E.coli.
Sequence : Full length.
Applications : Phosphatase Assay, Western Blot.
Storage And Stability : Store product at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
PDB rendering based on 1l8k. :

Gene Name : PTPN2 protein tyrosine phosphatase, non-receptor type 2 [ Homo sapiens ]
Synonyms : PTPN2; protein tyrosine phosphatase, non-receptor type 2; PTN2; PTPT; TCPTP; TC-PTP; TCELLPTP; Tyrosine-protein phosphatase non-receptor type 2; EC 3.1.3.48; T-cell protein-tyrosine phosphatase
Gene ID : 5771
mRNA Refseq : NM_002828
Protein Refseq : NP_002819
UniProt ID : P17706
Chromosome Location : 18p11.3-p11.2
MIM : 176887
Function : hydrolase activity; protein binding; non-membrane spanning protein tyrosine phosphatase activity

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