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Recombinant Mouse Ccl27a protein

Cat.No. : Ccl27a-118M
Product Overview : Recombinant Mouse Ccl27a protein was expressed in Escherichia coli.
  • Specification
  • Gene Information
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Description : Chemokine (C-C motif) ligand 27 (CCL27) is a small cytokine belonging to the CC chemokine family also known under the names IL-11 R-alpha-locus chemokine (ILC), Skinkine, ESkine and Cutaneous T-cell-attracting chemokine (CTACK). It is associated with homing of memory T lymphocytes to the skin, and plays a role in T cell-mediated inflammation of the skin. CCL27 is expressed in numerous tissues, including gonads, thymus, placenta and skin.
Source : E.coli
Species : Mouse
Form : Lyophilized from a 0.2μm filtered concentrated solution in 2 × PBS, pH 7.4, with 5% trehalose.
Bio-activity : Fully biologically active when compared to standard. The biological activity determined by a chemotaxis bioassay using human peripheral blood lymphocytes is in a concentration range of 10-100 ng/ml.
Molecular Mass : Approximately 10.9 kDa, a single, non-glycosylated polypeptide chain containing 95 amino acids.
Protein length : 95
AA Sequence : LPLPSSTSCCTQLYRQPLPSRLLRR IVHMELQEADGDCHLQAVVLHLARR SVCVHPQNRSLARWLERQGKRLQGT VPSLNLVLQKKMYSNPQQQN
Endotoxin : Less than 1 EU/µg of rMuCTACK/CCL27 as determined by LAL method.
Purity : >98% by SDS-PAGE and HPLC analysis.
Storage : Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 centigrade as supplied. 1 month, 2 to 8 centigrade under sterile conditions after reconstitution. 3 months, -20 to -70 centigrade under sterile conditions after reconstitution.
Reconstitution : We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1 % BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and stored at ≤-20 centigrade. Further dilutions should be made in appropriate buffered solutions.
Gene Name : Ccl27a
Official Symbol : Ccl27a
Synonyms : CCL27A; chemokine (C-C motif) ligand 27A; C-C motif chemokine 27; skinkine; skinskine; CC chemokine ILC; small inducible cytokine A27; small-inducible cytokine A27; IL-11 R-alpha-locus chemokine; small inducible cytokine A27a; chemokine (C-C motif) ligand 27; cutaneous T-cell-attracting chemokine; ALP; ILC; CTAK; CTACK; Ccl27; PESKY; ESkine; Scya27; Scya27a; AW558992; MGC130150;
Gene ID : 20301
mRNA Refseq : NM_001048179
Protein Refseq : NP_001041644
UniProt ID : Q9Z1X0

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (6)

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How can I detect the expression level of CCL27A protein? 11/27/2022

Expression level of CCL27A protein can be detected by immunohistochemistry, western blotting, and real-time PCR.

What cell surface receptors does CCL27A protein interact with? 10/12/2022

The CCL27A protein interacts with receptors on the surface of skin keratinocytes and immune cells, such as the CCR10 receptor.

What is the interaction between CCL27A protein and other proteins? 11/26/2021

Interaction between CCL27A protein and other proteins is regulated by the formation of complexes or the regulation of signal transduction pathways.

How is the expression of CCL27A protein regulated? 11/03/2021

The expression of CCL27A protein can be regulated by a variety of factors, including inflammatory factors, ultraviolet light, and infectious agents such as bacteria or viruses.

Can the function of CCL27A protein be studied by overexpression techniques? 01/05/2021

Function of the CCL27A protein can be studied by overexpression techniques, such as the use of gene transduction or viral transduction. These techniques can increase the expression level of CCL27A protein to observe its effects on skin inflammation and immune response, among other things.

How can the function of CCL27A protein be studied by gene knockout or knockdown techniques? 02/24/2020

The function of the CCL27A protein can be studied by gene knockout or knockdown techniques, such as using techniques such as CRISPR-Cas9 or RNAi. These techniques can create cellular models with missing or reduced CCL27A protein to observe its effects on skin inflammation and immune responses, among other things.

Customer Reviews (3)

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Reviews
09/08/2022

    CCL27A has good solubility and ion exchange ability, which is convenient for subsequent experimental treatment and purification.

    02/06/2022

      The stability of CCL27A has good adaptability under different temperature and pH conditions.

      04/29/2021

        When conducting experiments with CCL27A, clear and consistent results can be obtained for easy data analysis and interpretation.

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