Recombinant Mouse Ccl27a protein
Cat.No. : | Ccl27a-118M |
Product Overview : | Recombinant Mouse Ccl27a protein was expressed in Escherichia coli. |
- Specification
- Gene Information
- Related Products
Description : | Chemokine (C-C motif) ligand 27 (CCL27) is a small cytokine belonging to the CC chemokine family also known under the names IL-11 R-alpha-locus chemokine (ILC), Skinkine, ESkine and Cutaneous T-cell-attracting chemokine (CTACK). It is associated with homing of memory T lymphocytes to the skin, and plays a role in T cell-mediated inflammation of the skin. CCL27 is expressed in numerous tissues, including gonads, thymus, placenta and skin. |
Source : | E.coli |
Species : | Mouse |
Form : | Lyophilized from a 0.2μm filtered concentrated solution in 2 × PBS, pH 7.4, with 5% trehalose. |
Bio-activity : | Fully biologically active when compared to standard. The biological activity determined by a chemotaxis bioassay using human peripheral blood lymphocytes is in a concentration range of 10-100 ng/ml. |
Molecular Mass : | Approximately 10.9 kDa, a single, non-glycosylated polypeptide chain containing 95 amino acids. |
Protein length : | 95 |
AA Sequence : | LPLPSSTSCCTQLYRQPLPSRLLRR IVHMELQEADGDCHLQAVVLHLARR SVCVHPQNRSLARWLERQGKRLQGT VPSLNLVLQKKMYSNPQQQN |
Endotoxin : | Less than 1 EU/µg of rMuCTACK/CCL27 as determined by LAL method. |
Purity : | >98% by SDS-PAGE and HPLC analysis. |
Storage : | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 centigrade as supplied. 1 month, 2 to 8 centigrade under sterile conditions after reconstitution. 3 months, -20 to -70 centigrade under sterile conditions after reconstitution. |
Reconstitution : | We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1 % BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and stored at ≤-20 centigrade. Further dilutions should be made in appropriate buffered solutions. |
Gene Name : | Ccl27a |
Official Symbol : | Ccl27a |
Synonyms : | CCL27A; chemokine (C-C motif) ligand 27A; C-C motif chemokine 27; skinkine; skinskine; CC chemokine ILC; small inducible cytokine A27; small-inducible cytokine A27; IL-11 R-alpha-locus chemokine; small inducible cytokine A27a; chemokine (C-C motif) ligand 27; cutaneous T-cell-attracting chemokine; ALP; ILC; CTAK; CTACK; Ccl27; PESKY; ESkine; Scya27; Scya27a; AW558992; MGC130150; |
Gene ID : | 20301 |
mRNA Refseq : | NM_001048179 |
Protein Refseq : | NP_001041644 |
UniProt ID : | Q9Z1X0 |
Products Types
◆ Recombinant Protein | ||
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Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
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Q&As (6)
Ask a questionExpression level of CCL27A protein can be detected by immunohistochemistry, western blotting, and real-time PCR.
The CCL27A protein interacts with receptors on the surface of skin keratinocytes and immune cells, such as the CCR10 receptor.
Interaction between CCL27A protein and other proteins is regulated by the formation of complexes or the regulation of signal transduction pathways.
The expression of CCL27A protein can be regulated by a variety of factors, including inflammatory factors, ultraviolet light, and infectious agents such as bacteria or viruses.
Function of the CCL27A protein can be studied by overexpression techniques, such as the use of gene transduction or viral transduction. These techniques can increase the expression level of CCL27A protein to observe its effects on skin inflammation and immune response, among other things.
The function of the CCL27A protein can be studied by gene knockout or knockdown techniques, such as using techniques such as CRISPR-Cas9 or RNAi. These techniques can create cellular models with missing or reduced CCL27A protein to observe its effects on skin inflammation and immune responses, among other things.
Customer Reviews (3)
Write a reviewCCL27A has good solubility and ion exchange ability, which is convenient for subsequent experimental treatment and purification.
The stability of CCL27A has good adaptability under different temperature and pH conditions.
When conducting experiments with CCL27A, clear and consistent results can be obtained for easy data analysis and interpretation.
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