"TGFB2" Related Products


Recombinant Human Transforming Growth Factor, Beta 2, Monomeric Form

Cat. No. : TGFB2-467H
Product Overview : Recombinant human TGFβ-2 is a 25.4 kDa protein composed of two identical 112 amino acid peptide chains linked by a single disulfide bond. It was expressed inNicotiana benthamiana.Recombinant human TGFβ-2 is purified by sequential chromatography (FPLC). This product contains no animal –derived components or impurities.
Description : Transforming growth factor –β is a family of five related cytokines that have been shown on a wide variety of normal and neoplastic cells, indicating the importance of these homodimeric proteins as multi-functional regulators of cellular activity. The three mammalian isoforms of TGFβ (TGFβ-1, TGFβ-2 and TGFβ-3 ) signal through the same receptor and elicit similar biological responses. They are involved in physiological processes as embryogenesis, tissue remodelling and wound healing.
Source : Nicotiana benthamiana.
Molecular Formula : C 602H909N167O171S10.
Extinction Coefficient : E 0.1% 2.02 (A 280 nm).
P.I : 7.72.
Purity Assay : >98 % as determinate by SDS-PAGE gel.
Endotoxin Level : < 0.04 EU/ µg protein (LAL method).
Molecular Weight : recombinant protein 13.54 kDa, monomer form of 118 amino acid polypeptide chain.
Formulation : Lyophilized from a buffer of Tris HCl 0.05M pH 7.4.
Stotage And Stability : This lyophilized preparation is stable at 2-8° C, but should be kept at –20°C for long term storage. Repeated freezing and thawing is not recommended.
Gene Name : TGFB2 transforming growth factor, beta 2 [ Homo sapiens ]
Synonyms : TGFB2; Transforming growth factor beta 2; MGC116892; TGF-beta2; Transforming growth factor beta-2; TGF-beta-2; Glioblastoma-derived T-cell suppressor factor; G-TSF; BSC-1 cell growth inhibitor; Polyergin; Cetermin
Gene ID : 7042
mRNA Refseq : NM_001135599
Protein Refseq : NP_001129071
MIM : 190220
UniProt ID : P61812
Chromosome Location : 1q41
Pathway : Cell cycle; Chronic myeloid leukemia; Cytokine-cytokine receptor interaction; Dilated cardiomyopathy; Hypertrophic cardiomyopathy (HCM); MAPK signaling pathway; Pathways in cancer; Renal cell carcinoma; TGF-beta signaling pathway; Hemostasis
Function : beta-amyloid binding; cytokine activity; protein heterodimerization activity; growth factor activity; type II transforming growth factor beta receptor binding; receptor signaling protein serine/threonine kinase activity

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