"TGFB2" Related Products

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Recombinant Human Transforming Growth Factor, Beta 2, Monomeric Form

Cat. No.: TGFB2-467H
Product Overview: Recombinant human TGFβ-2 is a 25.4 kDa protein composed of two identical 112 amino acid peptide chains linked by a single disulfide bond. It was expressed inNicotiana benthamiana.Recombinant human TGFβ-2 is purified by sequential chromatography (FPLC). This product contains no animal –derived components or impurities.
Description: Transforming growth factor –β is a family of five related cytokines that have been shown on a wide variety of normal and neoplastic cells, indicating the importance of these homodimeric proteins as multi-functional regulators of cellular activity. The three mammalian isoforms of TGFβ (TGFβ-1, TGFβ-2 and TGFβ-3 ) signal through the same receptor and elicit similar biological responses. They are involved in physiological processes as embryogenesis, tissue remodelling and wound healing.
Source: Nicotiana benthamiana.
Molecular Formula: C 602H909N167O171S10.
Extinction Coefficient: E 0.1% 2.02 (A 280 nm).
P.I: 7.72.
Purity Assay: >98 % as determinate by SDS-PAGE gel.
Endotoxin Level: < 0.04 EU/ µg protein (LAL method).
Molecular Weight: recombinant protein 13.54 kDa, monomer form of 118 amino acid polypeptide chain.
Formulation: Lyophilized from a buffer of Tris HCl 0.05M pH 7.4.
Stotage And Stability: This lyophilized preparation is stable at 2-8° C, but should be kept at –20°C for long term storage. Repeated freezing and thawing is not recommended.
Gene Name: TGFB2 transforming growth factor, beta 2 [ Homo sapiens ]
Synonyms: TGFB2; Transforming growth factor beta 2; MGC116892; TGF-beta2; Transforming growth factor beta-2; TGF-beta-2; Glioblastoma-derived T-cell suppressor factor; G-TSF; BSC-1 cell growth inhibitor; Polyergin; Cetermin
Gene ID: 7042
mRNA Refseq: NM_001135599
Protein Refseq: NP_001129071
MIM: 190220
UniProt ID: P61812
Chromosome Location: 1q41
Pathway: Cell cycle; Chronic myeloid leukemia; Cytokine-cytokine receptor interaction; Dilated cardiomyopathy; Hypertrophic cardiomyopathy (HCM); MAPK signaling pathway; Pathways in cancer; Renal cell carcinoma; TGF-beta signaling pathway; Hemostasis
Function: beta-amyloid binding; cytokine activity; protein heterodimerization activity; growth factor activity; type II transforming growth factor beta receptor binding; receptor signaling protein serine/threonine kinase activity

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