Recombinant Human AGXT AGXT-26660TH

Recombinant Human AGXT


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Recombinant Human AGXT

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Cat.No. : AGXT-26660TH
Product Overview : Recombinant fragment of Human AGXT with N-terminal proprietary tag. Predicted MW 36.63 kDa.
Description : This gene is expressed only in the liver and the encoded protein is localized mostly in the peroxisomes, where it is involved in glyoxylate detoxification. Mutations in this gene, some of which alter subcellular targetting, have been associated with type I primary hyperoxaluria.
Protein length : 100 amino acids
Molecular Weight : 36.630kDa inclusive of tags
Source : Wheat germ
Tissue specificity : Liver.
Form : Liquid
Purity : Proprietary Purification
Storage buffer : pH: 8.00Constituents:0.79% Tris HCl, 0.3% Glutathione
Storage : Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles.
Sequence Similarities : Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.
Gene Name : AGXT alanine-glyoxylate aminotransferase [ Homo sapiens ]
Official Symbol : AGXT
Synonyms : AGXT; alanine-glyoxylate aminotransferase; SPAT; serine--pyruvate aminotransferase; AGT; AGT1; AGXT1; glycolicaciduria; L alanine: glyoxylate aminotransferase 1; oxalosis I; PH1; primary hyperoxaluria type 1; serine:pyruvate aminotransferase; SPT;
Gene ID : 189
mRNA Refseq : NM_000030
Protein Refseq : NP_000021
MIM : 604285
Uniprot ID : P21549
Chromosome Location : 2q37.3
Pathway : Alanine and aspartate metabolism, organism-specific biosystem; Alanine, aspartate and glutamate metabolism, organism-specific biosystem; Alanine, aspartate and glutamate metabolism, conserved biosystem; Glycine, serine and threonine metabolism, organism-specific biosystem; Glycine, serine and threonine metabolism, conserved biosystem;
Function : alanine-glyoxylate transaminase activity; amino acid binding; protein binding; protein homodimerization activity; pyridoxal phosphate binding;

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