Recombinant Human ALAS1
Cat.No. : | ALAS1-26883TH |
Product Overview : | Recombinant fragment of Human Alas1 with N terminal proprietary tag, 36.41kDa. |
- Specification
- Gene Information
- Related Products
Description : | Delta-aminolevulinate synthase (ALAS; EC 2.3.1.37) catalyzes the condensation of glycine with succinyl-CoA to form delta-aminolevulinic acid. This nuclear-encoded mitochondrial enzyme is the first and rate-limiting enzyme in the mammalian heme biosynthetic pathway. There are 2 tissue-specific isozymes: a housekeeping enzyme encoded by the ALAS1 gene and an erythroid tissue-specific enzyme encoded by ALAS2 (MIM 301300). |
Protein length : | 98 amino acids |
Molecular Weight : | 36.410kDa inclusive of tags |
Source : | Wheat germ |
Form : | Liquid |
Purity : | Proprietary Purification |
Storage buffer : | pH: 8.00Constituents:0.3% Glutathione, 0.79% Tris HCl |
Storage : | Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles. |
Sequences of amino acids : | MESVVRRCPFLSRVPQAFLQKAGKS LLFYAQNCPKMMEVGAKPAPRALST AAVHYQQIKETPPASEKDKTAKAKV QQTPDGSQQSPDGTQLPSGHPLP |
Sequence Similarities : | Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. |
Gene Name : | ALAS1 aminolevulinate, delta-, synthase 1 [ Homo sapiens ] |
Official Symbol : | ALAS1 |
Synonyms : | ALAS1; aminolevulinate, delta-, synthase 1; ALAS, ALAS3; 5-aminolevulinate synthase, nonspecific, mitochondrial; |
Gene ID : | 211 |
mRNA Refseq : | NM_000688 |
Protein Refseq : | NP_000679 |
MIM : | 125290 |
Uniprot ID : | P13196 |
Chromosome Location : | 3p21 |
Pathway : | FOXA2 and FOXA3 transcription factor networks, organism-specific biosystem; Glycine, serine and threonine metabolism, organism-specific biosystem; Glycine, serine and threonine metabolism, conserved biosystem; Heme Biosynthesis, organism-specific biosystem; Heme biosynthesis, organism-specific biosystem; |
Function : | 5-aminolevulinate synthase activity; pyridoxal phosphate binding; transferase activity, transferring acyl groups; transferase activity, transferring nitrogenous groups; |
Products Types
◆ Recombinant Protein | ||
Alas1-111R | Recombinant Rat Alas1 Protein, His&GST-tagged | +Inquiry |
ALAS1-266R | Recombinant Rat ALAS1 Protein, His (Fc)-Avi-tagged | +Inquiry |
ALAS1-11435Z | Recombinant Zebrafish ALAS1 | +Inquiry |
Alas1-4696M | Recombinant Mouse Alas1 protein, His&Myc-tagged | +Inquiry |
ALAS1-312H | Recombinant Human ALAS1 Protein, His-tagged | +Inquiry |
◆ Lysates | ||
ALAS1-8925HCL | Recombinant Human ALAS1 293 Cell Lysate | +Inquiry |
ALAS1-8924HCL | Recombinant Human ALAS1 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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