Recombinant Human ANGPTL3, FLAG-tagged
Welcome! For price inquiries, please feel free to contact us through the form below. We will get back to you as soon as possible.
| Cat.No. : | ANGPTL3-26574TH |
| Product Overview : | Recombinant full length Human ANGPTL3 fused at the C terminus to a DDDDK tag; mwt: 60 kDa by SDS PAGE. |
| Description : | The protein encoded by this gene is a member of the angiopoietin-like family of secreted factors. It is predominantly expressed in the liver, and has the characteristic structure of angiopoietins, consisting of a signal peptide, N-terminal coiled-coil domain and the C-terminal fibrinogen (FBN)-like domain. The FBN-like domain in angiopoietin-like 3 protein was shown to bind alpha-5/beta-3 integrins, and this binding induced endothelial cell adhesion and migration. This protein may also play a role in the regulation of angiogenesis. |
| Protein length : | 460 amino acids |
| Conjugation : | FLAG |
| Molecular Weight : | 60.000kDa inclusive of tags |
| Source : | HEK 293 cells |
| Tissue specificity : | Expressed principally in liver. Weakly expressed in kidney. |
| Biological activity : | Activates ERK phosphorylation in THP-1 cells. |
| Form : | Liquid |
| Purity : | >90% by SDS-PAGE |
| Storage buffer : | Preservative: NoneConstituents: PBS |
| Storage : | Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles. |
| Sequence Similarities : | Contains 1 fibrinogen C-terminal domain. |
| Gene Name : | ANGPTL3 angiopoietin-like 3 [ Homo sapiens ] |
| Official Symbol : | ANGPTL3 |
| Synonyms : | ANGPTL3; angiopoietin-like 3; ANGPT5; angiopoietin-related protein 3; angiopoietin 5; |
| Gene ID : | 27329 |
| mRNA Refseq : | NM_014495 |
| Protein Refseq : | NP_055310 |
| MIM : | 604774 |
| Uniprot ID : | Q9Y5C1 |
| Chromosome Location : | 1p31.1-p22.3 |
| Pathway : | Integrins in angiogenesis, organism-specific biosystem; |
| Function : | cell surface binding; enzyme inhibitor activity; growth factor activity; integrin binding; phospholipase inhibitor activity; |
◆ Recombinant Protein
| ANGPTL3-432H | Recombinant Human ANGPTL3 Protein (Met1-Glu460), His-tagged | +Inquiry |
| ANGPTL3-117H | Recombinant Human ANGPTL3 Protein, His-tagged | +Inquiry |
| ANGPTL3-783M | Recombinant Mouse ANGPTL3 Protein (Met1-Thr455), His-tagged | +Inquiry |
| ANGPTL3-176H | Recombinant Human ANGPTL3 protein, His-tagged | +Inquiry |
| ANGPTL3-555H | Recombinant Human ANGPTL3 protein, His-tagged | +Inquiry |
|
|
◆ Lysates
| ANGPTL3-8862HCL | Recombinant Human ANGPTL3 293 Cell Lysate | +Inquiry |
|
|
