"Il33" Related Products


Recombinant Murine Interleukin 33

Cat. No.: Il33-207M
Product Overview: Recombinant murine IL-33 is a 17.5 kDa protein containing 158 amino acid residues. It is expressed inE.Coli.
Description: IL-33 is a proinflammatory protein that shares structural and functional characteristics with the IL-1 cytokine family. It binds and signals through the IL-1RL1/ST2 receptor activating NF-kappaB and MAP kinases. IL-33 induces production of TH2 cell related cytokines, including IL-4, IL-5 and IL-13, and exerts multiple inflammation related bioactivities.
Source: E.Coli.
Purity: Greater than 98% (determined by SDS-PAGE and HPLC analysis).
Specific Activity: ≥ 2 x 10⁶units/mg.
Endotoxin Level: < 0.1 ng per µg of rMu IL-33 (1EU/µg).
Biological Activity: The ED50 as determined by the dose-dependent stimulation of the proliferation of murine D10S cells is ≤ 0.5 ng/ml, corresponding to a specific activity of ≥ 2 x 10⁶units/mg.
Formulation: Lyophilized from a sterile-filtered solution with no additives.
Reconstitution: Please Note: Always centrifuge product before opening vial. The lyophilized protein should be reconstituted with distilled, sterile water to a concentration of 0.1-1.0 mg/ml. For further dilution, carrier protein (0.1% BSA or HSA) should be added to avoid loss of bioactivity.
Storage: The lyophilized protein, though stable at room temperature for up to 3 weeks, is best stored desiccated at -20°C. Reconstituted protein should be used immediately or stored long-term in undiluted working aliquots at -20°C. For long-term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid repeated freeze-thaw cycles.
Gene Name: Il33 interleukin 33 [ Mus musculus ]
Synonyms: Il33; interleukin 33; Il-33; Il1f11; NF-HEV; 9230117N10Rik; nuclear factor from high endothelial venules
Gene ID: 77125
mRNA Refseq: NM_001164724
Protein Refseq: NP_001158196
UniProt ID: Q8BVZ5
Chromosome Location: 19 C2
Function: cytokine activity

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