"BAG1" Related Products

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Recombinant Human BCL2-Associated Athanogene, GST-tagged

Cat. No. : BAG1-1434H
Product Overview : Recombinant human BAG1 (72-end) was expressed inE. colicells using an N-terminal GST tag. MW = 66kDa.
Description : BAG1 (also known as BCL2-associated athanogene) is a membrane protein rich in glutamic acid residues that binds to BCL2 and blocks apoptosis or programmed cell death. The BAG1-BCL2 complex enhances the anti-apoptotic effects of BCL2 and represents a link between growth factor receptors and anti-apoptotic mechanisms. Overexpression of BAG1 in 3T3 fibroblasts prevents apoptosis in the presence of low serum. BAG1 has also been shown to interact with activated glucocorticoid, androgen, estrogen and progesterone receptors. Binding to these receptors by BAG1 is dependent on receptor activation.
Source : E. coli.
Sequence : 72-end.
Applications : Western Blot.
Storage And Stability : Store product at -70℃. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
PDB rendering based on 1hx1. :

Gene Name : BAG1 BCL2-associated athanogene [ Homo sapiens ]
Synonyms : BAG1; BCL2-associated athanogene; RAP46; BAG-1; HAP; BCL2-associated athanogene 1; Bcl-2-associated athanogene 1; Glucocorticoid receptor-associated protein RAP46
Gene ID : 573
mRNA Refseq : NM_004323
Protein Refseq : NP_004314
MIM : 601497
UniProt ID : Q99933
Chromosome Location : 9p12
Function : protein binding; receptor signaling protein activity

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