"PPM1F" Related Products

Recombinant Human PPM1F,GST-tagged

Cat. No. : PPM1F-1439H
Product Overview : Recombinant full-length human CaMKPase was expressed inE. colicells using an N-terminal GST tag. MW = 74kDa.
Description : CaMKPase is a member of the PP2C family of Ser/Thr protein phosphatases that dephosphorylate and regulate the multifunctional Ca2+/calmodulin-dependent protein kinases (CaMKs). The multifunctional CaMKs mediate cellular responses induced by increases in second messenger Ca2+ and have been implicated in the control of synaptic transmission, gene transcription, cell growth and contraction of cardiac and smooth muscles. Overexpression of CaMKPase has been shown to mediate caspase-dependent apoptosis. CaMKPase can also interact with the Rho guanine nucleotide exchange factors (PIX) thereby blocking the effects of p21-activated kinase 1 (PAK1).
Source : E. coli.
Sequence : Full-length.
Applications : Western Blot.
Storage And Stability : Store product at -70℃. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
Gene Name : PPM1F protein phosphatase 1F (PP2C domain containing) [ Homo sapiens ]
Synonyms : PPM1F; protein phosphatase 1F (PP2C domain containing); CAMKP; FEM-2; POPX2; hFEM-2; CaMKPase; KIAA0015
Gene ID : 9647
mRNA Refseq : NM_014634
Protein Refseq : NP_055449
UniProt ID : P49593
Chromosome Location : 22q11.22
Function : hydrolase activity; magnesium ion binding; manganese ion binding; protein serine/threonine phosphatase activity

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