||Recombinant Human BMP7. A 28.8 kDa homodimeric glycoprotein consisting of two 116 amino acid subunits, corresponding to amino acid residues 315 to 431 of the full-length BMP7 precursor.
||The bone morphogenetic proteins (BMPs) are a family of secreted signaling molecules that can induce ectopic bone growth. Many BMPs are part of the transforming growth factor-beta (TGFB) superfamily. BMPs were originally identified by an ability of demineralized bone extract to induce endochondral osteogenesis in vivo in an extraskeletal site. Based on its expression early in embryogenesis, the BMP encoded by this gene has a proposed role in early development and possible bone inductive activity.
||Expressed in the kidney and bladder. Lower levels seen in the brain.
||Lyophilised:It is recommended that further dilutions be made in PBS containing 2 mg/ml albumin and stored at -200C for future use.
||Preservative: NoneEndotoxin level is less than 0.1 ng per μg (1EU/μg).
||Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
|Sequences of amino acids:
||MANVAENSSS DQRQACKKHE LYVSFRDLGW QDWIIAPEGY AAYYCEGECA FPLNSYMNAT NHAIVQTLVH FINPETVPKP CCAPTQLNAI SVLYFDDSSN VILKKYRNMV VRACGCH
||Belongs to the TGF-beta family.