Recombinant Human BMP8B


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Recombinant Human BMP8B

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Cat.No. : BMP8B-27490TH
Product Overview : Recombinant fragment of Human BMP8 with a N terminal proprietary tag; Predicted MW 35.42 kDa.
Description : The bone morphogenetic proteins (BMPs) are a family of secreted signaling molecules that can induce ectopic bone growth. Many BMPs are part of the transforming growth factor-beta (TGFB) superfamily. BMPs were originally identified by an ability of demineralized bone extract to induce endochondral osteogenesis in vivo in an extraskeletal site. Based on its expression early in embryogenesis, the BMP encoded by this gene has a proposed role in early development. In addition, the fact that this BMP is closely related to BMP5 and BMP7 has led to speculation of possible bone inductive activity.
Protein length : 89 amino acids
Molecular Weight : 35.420kDa inclusive of tags
Source : Wheat germ
Form : Liquid
Purity : Proprietary Purification
Storage buffer : pH: 8.00Constituents:0.79% Tris HCl, 0.3% Glutathione
Storage : Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles.
Sequence Similarities : Belongs to the TGF-beta family.
Gene Name : BMP8B bone morphogenetic protein 8b [ Homo sapiens ]
Official Symbol : BMP8B
Synonyms : BMP8B; bone morphogenetic protein 8b; BMP8, bone morphogenetic protein 8 (osteogenic protein 2); bone morphogenetic protein 8B; OP 2; osteogenic protein 2;
Gene ID : 656
mRNA Refseq : NM_001720
Protein Refseq : NP_001711
MIM : 602284
Uniprot ID : P34820
Chromosome Location : 1p35-p32
Pathway : Hedgehog signaling pathway, organism-specific biosystem; Hedgehog signaling pathway, conserved biosystem; TGF-beta signaling pathway, organism-specific biosystem; TGF-beta signaling pathway, conserved biosystem;
Function : cytokine activity; growth factor activity;
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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