Recombinant Human CA3 CA3-27266TH

Recombinant Human CA3

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Recombinant Human CA3

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Cat.No. : CA3-27266TH
Product Overview : Recombinant full length Carbonic Anhydrase III protein (Human)
Description : Carbonic anhydrase III (CAIII) is a member of a multigene family (at least six separate genes are known) that encodes carbonic anhydrase isozymes. These carbonic anhydrases are a class of metalloenzymes that catalyze the reversible hydration of carbon dioxide and are differentially expressed in a number of cell types. The expression of the CA3 gene is strictly tissue specific and present at high levels in skeletal muscle and much lower levels in cardiac and smooth muscle. A proportion of carriers of Duchenne muscle dystrophy have a higher CA3 level than normal. The gene spans 10.3 kb and contains seven exons and six introns.
Source : E. coli
Tissue specificity : Muscle specific.
Form : Liquid
Purity : >90% by SDS-PAGE
Storage : Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Sequence Similarities : Belongs to the alpha-carbonic anhydrase family.
Gene Name : CA3 carbonic anhydrase III, muscle specific [ Homo sapiens ]
Official Symbol : CA3
Synonyms : CA3; carbonic anhydrase III, muscle specific; carbonic anhydrase 3; CAIII; Car3;
Gene ID : 761
mRNA Refseq : NM_005181
Protein Refseq : NP_005172
MIM : 114750
Uniprot ID : P07451
Chromosome Location : 8q21.2
Pathway : Nitrogen metabolism, organism-specific biosystem; Nitrogen metabolism, conserved biosystem;
Function : carbonate dehydratase activity; lyase activity; metal ion binding; nickel ion binding; zinc ion binding;

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