"CDC25C" Related Products


Recombinant Human CDC25C

Cat.No.: CDC25C-27900TH
Product Overview: Recombinant full length Human Cdc25C with N-terminal proprietary tag, 84kDa.
Description: This gene is highly conserved during evolution and it plays a key role in the regulation of cell division. The encoded protein is a tyrosine phosphatase and belongs to the Cdc25 phosphatase family. It directs dephosphorylation of cyclin B-bound CDC2 and triggers entry into mitosis. It is also thought to suppress p53-induced growth arrest. Multiple alternatively spliced transcript variants of this gene have been described, however, the full-length nature of many of them is not known.
Protein length: 473 amino acids
Molecular Weight: 84.000kDa inclusive of tags
Source: Baculovirus infected sf9 cells
Biological activity: The Specific activity of CDC25C-27900TH was determined to be 22 nmol/min/mg.
Form: Liquid
Purity: by SDS-PAGE
Storage buffer: Preservative: NoneConstituents: 25% Glycerol, 50mM Tris HCl, 150mM Sodium chloride, 10mM Glutathione, 0.25mM DTT, 0.1mM EDTA, 0.1mM PMSF, pH 7.5
Storage: Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles.
Sequence Similarities: Belongs to the MPI phosphatase family.Contains 1 rhodanese domain.
Gene Name: CDC25C cell division cycle 25 homolog C (S. pombe) [ Homo sapiens ]
Official Symbol: CDC25C
Synonyms: CDC25C; cell division cycle 25 homolog C (S. pombe); CDC25, cell division cycle 25 homolog C (S. cerevisiae) , cell division cycle 25C; M-phase inducer phosphatase 3; PPP1R60; protein phosphatase 1; regulatory subunit 60;
Gene ID: 995
mRNA Refseq: NM_001790
Protein Refseq: NP_001781
MIM: 157680
Uniprot ID: P30307
Chromosome Location: 5q31
Pathway: Activation of ATR in response to replication stress, organism-specific biosystem; Cell Cycle Checkpoints, organism-specific biosystem; Cell Cycle, Mitotic, organism-specific biosystem; Cell cycle, organism-specific biosystem; Cell cycle, organism-specific biosystem;
Function: WW domain binding; hydrolase activity; protein binding; protein tyrosine phosphatase activity;

Online Inquiry

Note: There will be extra charge for optional service!

Please input "biomart" as verification code. Please review Creative BioMart's privacy policy for more information

Optional requirements on this protein    +Expand

Price Inquiry

Welcome! For price inquiries, please feel free to contact us through the form below. We will get back to you as soon as possible.