Recombinant Human CDC42, T7 -tagged
Cat.No. : | CDC42-26651TH |
Product Overview : | Recombinant full length mature human CDC42 fused to T7 tag at N-terminus; amino acids 1-188 , 22.4kDa. |
- Specification
- Gene Information
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Description : | The protein encoded by this gene is a small GTPase of the Rho-subfamily, which regulates signaling pathways that control diverse cellular functions including cell morphology, migration, endocytosis and cell cycle progression. This protein is highly similar to Saccharomyces cerevisiae Cdc 42, and is able to complement the yeast cdc42-1 mutant. The product of oncogene Dbl was reported to specifically catalyze the dissociation of GDP from this protein. This protein could regulate actin polymerization through its direct binding to Neural Wiskott-Aldrich syndrome protein (N-WASP), which subsequently activates Arp2/3 complex. Alternative splicing of this gene results in multiple transcript variants. |
Conjugation : | T7 |
Source : | E. coli |
Form : | Liquid |
Purity : | >95% by SDS-PAGE |
Storage buffer : | Preservative: NoneConstituents: 10% Glycerol, 20mM Tris HCl, 2mM EDTA, 1mM DTT, pH 8.0 |
Storage : | Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles. |
Sequences of amino acids : | MASMTGGQQM GRGSHMQTIK CVVVGDGAVG KTCLLISYTT NKFPSEYVPT VFDNYAVTVM IGGEPYTLGL FDTAGQEDYD RLRPLSYPQT DVFLVCFSVV SPSSFENVKE KWVPEITHHC PKTPFLLVGT QIDLRDDPST IEKLAKNKQK PITPETAEKL ARDLKAVKYV ECSALTQKGL KNVFDEAILA ALEPPEPKKS RRC |
Sequence Similarities : | Belongs to the small GTPase superfamily. Rho family. CDC42 subfamily. |
Gene Name : | CDC42 cell division cycle 42 (GTP binding protein, 25kDa) [ Homo sapiens ] |
Official Symbol : | CDC42 |
Synonyms : | CDC42; cell division cycle 42 (GTP binding protein, 25kDa); cell division cycle 42 (GTP binding protein, 25kD); cell division control protein 42 homolog; CDC42Hs; G25K; |
Gene ID : | 998 |
mRNA Refseq : | NM_001039802 |
Protein Refseq : | NP_001034891 |
MIM : | 116952 |
Uniprot ID : | P60953 |
Chromosome Location : | 1p36.1 |
Function : | GTP binding; GTP-dependent protein binding; GTPase activity; GTPase activity; mitogen-activated protein kinase kinase kinase binding; |
Products Types
◆ Recombinant Protein | ||
CDC42-589R | Recombinant Rhesus Macaque CDC42 Protein, His (Fc)-Avi-tagged | +Inquiry |
CDC42-1806H | Recombinant Human CDC42 protein(Met1-Cys188), GST-tagged | +Inquiry |
CDC42-143C | Recombinant Cynomolgus Monkey CDC42 Protein, His (Fc)-Avi-tagged | +Inquiry |
Cdc42-856M | Recombinant Mouse Cdc42 Protein, MYC/DDK-tagged | +Inquiry |
CDC42-0934H | Recombinant Human CDC42 Protein, GST-Tagged | +Inquiry |
◆ Lysates | ||
CDC42-7655HCL | Recombinant Human CDC42 293 Cell Lysate | +Inquiry |
◆ Assay kits | ||
Kit-0191 | Cdc42 G-LISA Activation Assay Kit (Colorimetric) II | +Inquiry |
Kit-0190 | Cdc42 G-LISA Activation Assay Kit (Colorimetric) | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (7)
Ask a questionCDC42 controls cytoskeletal dynamics, leading to changes in cell shape and movement.
CDC42 is important in neuronal development and plays a role in forming and remodeling synaptic connections.
Changes in CDC42 activity can impact aging processes and contribute to the development of age-related diseases.
CDC42 facilitates cancer progression by enhancing cell migration, invasion, and metastatic potential.
CDC42 aids in wound healing and regeneration by guiding cell migration and tissue restructuring.
CDC42 is crucial for cell division and cycle progression, coordinating cellular events for proper division.
CDC42 regulates immune cell movement and activation, essential for immune response and surveillance.
Customer Reviews (3)
Write a reviewReliable protein crystallography, essential for structural studies.
Exceptional protein engineering services, meets our lab's needs.
Efficient peptide synthesis, crucial for our peptide research.
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