Recombinant Human COX4I1

• Cat.No.: COX4I1-26361TH
• Product Overview: Recombinant full length, Human COX IV with proprietary tag, Predicted MW 44.33 kDa.

Specification

• Description: Cytochrome c oxidase (COX) is the terminal enzyme of the mitochondrial respiratory chain. It is a multi-subunit enzyme complex that couples the transfer of electrons from cytochrome c to molecular oxygen and contributes to a proton electrochemical gradient across the inner mitochondrial membrane. The complex consists of 13 mitochondrial- and nuclear-encoded subunits. The mitochondrially-encoded subunits perform the electron transfer and proton pumping activities. The functions of the nuclear-encoded subunits are unknown but they may play a role in the regulation and assembly of the complex. This gene encodes the nuclear-encoded subunit IV isoform 1 of the human mitochondrial respiratory chain enzyme. It is located at the 3 of the NOC4 (neighbor of COX4) gene in a head-to-head orientation, and shares a promoter with it.
• Protein length: 169 amino acids
• Molecular Weight: 44.330kDa inclusive of tags
• Source: Wheat germ
• Tissue specificity: Ubiquitous.
• Form: Liquid
• Purity: Proprietary Purification
• Storage buffer: pH: 8.00Constituents:0.31% Glutathione, 0.79% Tris HCl
• Storage: Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles.
• Sequences of amino acids: MLATRVFSLVGKRAISTSVCVRAHE SVVKSEDFSLPAYMDRRDHPLPEVA HVKHLSASQKALKEKEKASWSSLSM DEKVELYRIKFKESFAEMNRGSNEW KTVVGGAMFFIGFTALVIMWQKHYV YGPLPQSFDKEWVAKQTKRMLDMKV NPIQGLASKWDYEKNEWKK
• Sequence Similarities: Belongs to the cytochrome c oxidase IV family.

Gene Information

• Gene Name: COX4I1 cytochrome c oxidase subunit IV isoform 1 [ Homo sapiens ]
• Official Symbol: COX4I1
• Synonyms: COX4I1; cytochrome c oxidase subunit IV isoform 1; COX4, cytochrome c oxidase subunit IV; cytochrome c oxidase subunit 4 isoform 1, mitochondrial; COX4 1
• Gene ID: 1327
• mRNA Refseq: NM_001861
• Protein Refseq: NP_001852
• MIM: 123864
• Uniprot ID: P13073
• Chromosome Location: 16q24.1
• Pathway: Alzheimers disease, organism-specific biosystem; Alzheimers disease, conserved biosystem; Cardiac muscle contraction, organism-specific biosystem; Cardiac muscle contraction, conserved biosystem; Cytochrome c oxidase, organism-specific biosystem
• Function: cytochrome-c oxidase activity