Recombinant Human CX3CR1

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Recombinant Human CX3CR1

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Cat.No. : CX3CR1-28062TH
Product Overview : Recombinant full length Human CX3CR1 protein with a proprietary tag; predicted mwt: 65.12 kDa.
Description : Fractalkine is a transmembrane protein and chemokine involved in the adhesion and migration of leukocytes. The protein encoded by this gene is a receptor for fractalkine. The encoded protein also is a coreceptor for HIV-1, and some variations in this gene lead to increased susceptibility to HIV-1 infection and rapid progression to AIDS. Four transcript variants encoding two different isoforms have been found for this gene.
Protein length : 355 amino acids
Molecular Weight : 65.120kDa
Source : Wheat germ
Tissue specificity : Expressed in lymphoid and neural tissues.
Form : Liquid
Purity : Proprietary Purification
Storage buffer : Constituents:0.79% Tris HCl, 0.31% GlutathioneNote: Reduced Glutathione
Storage : Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles.
Sequences of amino acids : MDQFPESVTE NFEYDDLAEA CYIGDIVVFG TVFLSIFYSV IFAIGLVGNL LVVFALTNSK KPKSVTDIYL LNLALSDLLF VATLPFWTHY LINEKGLHNA MCKFTTAFFF IGFFGSIFFI TVISIDRYLA IVLAANSMNN RTVQHGVTIS LGVWAAAILV AAPQFMFTKQ KENECLGDYP EVLQEIWPVL RNVETNFLGF LLPLLIMSYC YFRIIQTLFS CKNHKKAKAI KLILLVVIVF FLFWTPYNVM IFLETLKLYD FFPSCDMRKD LRLALSVTET VAFSHCCLNP LIYAFAGEKF RRYLYHLYGK CLAVLCGRSV HVDFSSSESQ RSRHGSVLSS NFTYHTSDGD ALLLL
Sequence Similarities : Belongs to the G-protein coupled receptor 1 family.
Gene Name : CX3CR1 chemokine (C-X3-C motif) receptor 1 [ Homo sapiens ]
Official Symbol : CX3CR1
Synonyms : CX3CR1; chemokine (C-X3-C motif) receptor 1; chemokine (C X3 C) receptor 1 , CMKBRL1, GPR13; CX3C chemokine receptor 1; CCRL1; CMKDR1; V28;
Gene ID : 1524
mRNA Refseq : NM_001171171
Protein Refseq : NP_001164642
MIM : 601470
Uniprot ID : P49238
Chromosome Location : 3p21.3
Pathway : Chemokine receptors bind chemokines, organism-specific biosystem; Chemokine signaling pathway, organism-specific biosystem; Chemokine signaling pathway, conserved biosystem; Class A/1 (Rhodopsin-like receptors), organism-specific biosystem; Cytokine-cytokine receptor interaction, organism-specific biosystem;
Function : C-X3-C chemokine receptor activity; G-protein coupled receptor activity; chemokine receptor activity; protein binding; receptor activity;
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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