|Product Overview :
||Recombinant full length Human DPP9 with N terminal proprietary tag expressed in a Baculovirus infected Sf9 cell expression system, 122.6 kDa.
||This gene encodes a protein that is a member of the S9B family in clan SC of the serine proteases. The protein has been shown to have post-proline dipeptidyl aminopeptidase activity, cleaving Xaa-Pro dipeptides from the N-termini of proteins. Although the activity of this protein is similar to that of dipeptidyl peptidase 4 (DPP4), it does not appear to be membrane bound. In general, dipeptidyl peptidases appear to be involved in the regulation of the activity of their substrates and have been linked to a variety of diseases including type 2 diabetes, obesity and cancer. Several transcript variants of this gene have been described but not fully characterized.
|Tissue specificity :
||Ubiquitously expressed, with highest levels in liver, heart and muscle, and lowest levels in brain.
|Biological activity :
||Specific Activity: 536 U/ug. One U =1 pmol/min.
|Storage buffer :
||Preservative: NoneConstituents: 50% Glycerol, 0.05% Tween 20, 3mM DTT, 25mM Tris HCl, 100mM Sodium chloride, pH 8.0
||Aliquot and store at -80°C. Avoid repeated freeze / thaw cycles.
|Sequence Similarities :
||Belongs to the peptidase S9B family. DPPIV subfamily.