Recombinant Human EDNRA
Cat.No. : | EDNRA-28562TH |
Product Overview : | Recombinant fragment of Human Endothelin A Receptor with N terminal proprietary tag, 32.56kDa inclusive of tag. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes the receptor for endothelin-1, a peptide that plays a role in potent and long-lasting vasoconstriction. This receptor associates with guanine-nucleotide-binding (G) proteins, and this coupling activates a phosphatidylinositol-calcium second messenger system. Polymorphisms in this gene have been linked to migraine headache resistance. Alternative splicing results in multiple transcript variants. |
Protein length : | 63 amino acids |
Molecular Weight : | 32.560kDa inclusive of tags |
Source : | Wheat germ |
Tissue specificity : | Isoform 1, isoform 3 and isoform 4 are expressed in a variety of tissues, with highest levels in the aorta and cerebellum, followed by lung, atrium and cerebral cortex, lower levels in the placenta, kidney, adrenal gland, duodenum, colon, ventricle and li |
Form : | Liquid |
Purity : | Proprietary Purification |
Storage buffer : | pH: 8.00Constituents:0.3% Glutathione, 0.79% Tris HCl |
Storage : | Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles. |
Sequences of amino acids : | VISDNPERYSTNLSNHVDDFTTFRG TELSFLVTTHQPTNLVLPSNGSMHN YCPQQTKITSAFK |
Sequence Similarities : | Belongs to the G-protein coupled receptor 1 family. Endothelin receptor subfamily. EDNRA sub-subfamily. |
Gene Name : | EDNRA endothelin receptor type A [ Homo sapiens ] |
Official Symbol : | EDNRA |
Synonyms : | EDNRA; endothelin receptor type A; endothelin-1 receptor; |
Gene ID : | 1909 |
mRNA Refseq : | NM_001166055 |
Protein Refseq : | NP_001159527 |
MIM : | 131243 |
Uniprot ID : | P25101 |
Chromosome Location : | 4 |
Pathway : | Calcium signaling pathway, organism-specific biosystem; Calcium signaling pathway, conserved biosystem; Class A/1 (Rhodopsin-like receptors), organism-specific biosystem; EGFR-dependent Endothelin signaling events, organism-specific biosystem; Endothelins, organism-specific biosystem; |
Function : | G-protein coupled receptor activity; endothelin receptor activity; phosphatidylinositol phospholipase C activity; receptor activity; signal transducer activity; |
Products Types
◆ Recombinant Protein | ||
EDNRA-1405H | Recombinant Human EDNRA Protein, His-tagged | +Inquiry |
EDNRA-1205R | Recombinant Rhesus Macaque EDNRA Protein, His (Fc)-Avi-tagged | +Inquiry |
EDNRA-2641M | Recombinant Mouse EDNRA Protein, His (Fc)-Avi-tagged | +Inquiry |
EDNRA-22H | Recombinant Human EDNRA Protein | +Inquiry |
EDNRA-3058H | Recombinant Human EDNRA Protein, GST-tagged | +Inquiry |
◆ Lysates | ||
EDNRA-6718HCL | Recombinant Human EDNRA 293 Cell Lysate | +Inquiry |
◆ Assay kits | ||
Kit-1229 | EDNRA CHO-K1 β-Arrestin GPCR Assay Kit | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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